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Is There More to Within-plant Variation in Seed Size than Developmental Noise?

Within-plant variation in seed size may merely reflect developmental instability, or it may be adaptive in facilitating diversifying bet-hedging, that is, production of phenotypically diverse offspring when future environments are unpredictable. To test the latter hypothesis, we analyzed patterns of variation in seed size in 11 populations of the perennial vine Dalechampia scandens grown in a comm

Association between SARS-CoV-2 and exposure risks in health care workers and university employees – a cross-sectional study

BackgroundIn health care workers SARS-CoV-2 has been shown to be an occupational health risk, often associated with transmission between health care workers. Yet, insufficient information on transmission dynamics has been presented to elucidate the precise risk factors for contracting SARS-CoV-2 in this group.MethodsIn this cross-sectional study, we investigated association between questionnaire a

Rapid subgenus identification of human adenovirus isolates by a general PCR

In most clinical situations involving adenovirus infection, subgenus (subgroup) identification of an adenovirus isolate is as informative as a finer identification by serotype. A PCR method which allows the identification of human adenovirus isolates as members of subgenera A, B:1, B:2, C, D, E, or F is described. It is based on a simple (nonnested) PCR using primers which bind to regions immediat

Dopaminergic neurons lacking Caspase-3 avoid apoptosis but undergo necrosis after MPTP treatment inducing a Galectin-3-dependent selective microglial phagocytic response

Parkinson’s Disease (PD) is a progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the Substantia nigra pars compacta (SNpc). Apoptosis is thought to play a critical role in the progression of PD, and thus understanding the effects of antiapoptotic strategies is crucial for developing potential therapies. In this study, we developed a unique genetic model to

Continuous feedback protocols for cooling and trapping a quantum harmonic oscillator

Quantum technologies and experiments often require preparing systems in low-temperature states. Here we investigate cooling schemes using feedback protocols modeled with a quantum Fokker-Planck master equation (QFPME) recently derived by Annby-Andersson et al. [Phys. Rev. Lett. 129, 050401 (2022)0031-900710.1103/PhysRevLett.129.050401]. This equation describes systems under continuous weak measure

Flood vulnerability mapping in an urban area with high levels of impermeable coverage in southern Brazil

Flooding is one of the main social impacts in urban areas, especially in larger, densely impermeable cities. Therefore, developing studies capable of identifying areas that are vulnerable to this type of event is crucial to provide early warning and a quick and effective response to reduce damages. Thus, this study sought to identify areas vulnerable to flood in the Igapó Lake Basin, a densely urb

Preoperative Group Consultation Prior to Surgery for Colorectal Cancer—an Explorative Study of a New Patient Education Method

Abstract: Patients with colorectal cancer may lack information about the disease and treatment. In 2017, a group consultation before start of surgery was introduced at a university hospital in western Sweden to inform about the disease, treatment, and ongoing scientific studies. The primary aim of this study was to explore the experience of the patients attending the group consultation. Based on s

Management of aortic disease in children with FBN1-related Marfan syndrome: a joint statement from the paediatric subgroup of the European Reference Network of Vascular Diseases (VASCERN, Heritable Thoracic Aortic Disease working group) and the Association for European Paediatric and Congenital Cardiology (AEPC)

Marfan syndrome (MFS) is a hereditary connective tissue disorder with an estimated prevalence of 1:5000–1:10 000 individuals. It is a pleiotropic disease characterized by specific ocular, cardiovascular, and skeletal features. The most common cardiovascular complication is aortic root dilatation which untreated can lead to life-threatening aortic root dissection, mainly occurring in adult patients

Framing adaptive capacity of coastal communities: A review of the role of scientific framing in indicator-based adaptive capacity assessments in coastal social-ecological systems

In the current context of climate and anthropogenic change, assessing the adaptive capacity of coastal communities, i.e., their ability to adapt, navigate and/or recover from the impacts of change is key in coastal management and decision-making processes. Framing in adaptive capacity assessments (i.e., what is highlighted) influences how coastal communities’ adaptive capacity is perceived and und

Integration of attractive and defensive phytochemicals is unlikely to constrain chemical diversification in a perennial herb

Diversification of plant chemical phenotypes is typically associated with spatially and temporally variable plant–insect interactions. Floral scent is often assumed to be the target of pollinator-mediated selection, whereas foliar compounds are considered targets of antagonist-mediated selection. However, floral and vegetative phytochemicals can be biosynthetically linked and may thus evolve as i

Role of Iodine-Assisted Aerosol Particle Formation in Antarctica

New particle formation via the ion-mediated sulfuric acid and ammonia molecular clustering mechanism remains the most widely observed and experimentally verified pathway. Recent laboratory and molecular level observations indicate iodine-driven nucleation as a potentially important source of new particles, especially in coastal areas. In this study, we assess the role of iodine species in particle

Deep-learning-powered data analysis in plankton ecology

The implementation of deep learning algorithms has brought new perspectives to plankton ecology. Emerging as an alternative approach to established methods, deep learning offers objective schemes to investigate plankton organisms in diverse environments. We provide an overview of deep-learning-based methods including detection and classification of phytoplankton and zooplankton images, foraging an

Therapist-guided and parent-guided internet-delivered behaviour therapy for paediatric Tourette's disorder : A pilot randomised controlled trial with long-term follow-up

Objective Behaviour therapy (BT) for Tourette's disorder (TD) and persistent (chronic) motor or vocal tic disorder (PTD) is rarely available. We evaluated the feasibility of adapting two existing BT protocols for TD/PTD (habit reversal training (HRT) and exposure and response prevention (ERP)) into a therapist-guided and parent-guided online self-help format. Design A pilot, single-blind, parallel

Displaced Supracondylar Humerus Fractures in Toddlers

Gartland type III fracture is the most troublesome type of supracondylar humerus fracture. These injuries most often occur in school age children, but they are seen in pediatric patients of all ages. The goal of this study was to analyze toddlers with Gartland type III fractures to identify clinically significant differences compared with older children. A retrospective cohort study was conducted

A Quality Assessment of the ARM-Net Registry Design and Data Collection

Background: Registries are important in rare disease research. The Anorectal Malformation Network (ARM-Net) registry is a well-established European patient registry collecting demographic, clinical, and functional outcome data. We assessed the quality of this registry through review of the structure, data elements, collected data, and user experience. Material and methods: Design and data elements

Looking back to move forwards: A social and cultural history of home heating (JUSTHEAT) : Interim findings from the first round of case studies

This short report is one of a series of outputs to flow from the international,interdisciplinary project ‘Looking back to move forwards: a social and cultural historyof home heating’ (JUSTHEAT), funded through the Collaboration of Humanities andSocial Sciences in Europe (CHANSE) initiative, which began in 2022 and runs until2025. Within this project, we aim to understand how major changes to home

Movements in the dark : flying, landing and walking in insects

Att färdas i mörker: insekters lösningar, vinster och kostnaderIn sin ständiga jakt på mat måste många insekter undvika att krocka med grenar, stenar och blad, samt färdas i en lämplig kompassriktning. Åtskilliga insekter använder sin syn för att kontrollera detta. En nektarsökande humla, till exempel, reglerar sin flyghastighet efter hur snabbt föremål i omgivningen rör sig över dess ögon. Denna Flying, as well as walking insects rely on vision to regulate locomotion, even in the dark when the visual system is much less reliable. To manage visual control of these behaviours at low light intensities, many insects have evolved optical adaptations, such as larger facet lenses and wider rhabdoms, and neural adaptations, such as spatial and temporal summation, to increase their visual sensitiv

Prophylactic fenoldopam for renal protection in sepsis: a randomized, double blind, placebo-controlled pilot trial

OBJECTIVE: Acute renal failure is common in septic patients. Fenoldopam, a dopamine-1 receptor agonist, increases renal blood flow and may, therefore, reduce the risk of acute renal failure in such patients. Accordingly, we sought to determine the safety and efficacy of fenoldopam for the prevention of acute renal failure in septic patients. DESIGN: Prospective, double-blind, placebo-controlled t