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Background and purpose: The purpose of this work was a comparison of realistic IMRT plans based on the same CT-image data set and a common predefined set of dose objectives for the planning target volume and the organs at risk. This work was part of the larger European QUASIMODO IMRT verification project. Materials and methods: Eleven IMRT. plans were produced by nine different European groups, ea

Purpose: To compare the outcome of endovascular aneurysm repair (EVAR) versus conventional open repair (OR) in patients with a short, angulated or otherwise challenging proximal neck. Methods: The definition of a challenging proximal neck was based on diameter (>= 28 mm), length (<= 115 mm), angulation (>= 60 degrees), shape (reverse tapered or bulging), and thrombus lining (>50%). Between January

A series of resonant Auger-electron spectra excited at selected photon energies across the O 1s -> Rydberg resonances in O-2 has been measured. Applying a spectator-electron shake relaxation model originally introduced for atomic resonant Auger-electron spectra, and using, to a large extent, the assignments for the core-excited resonances available from the literature, many of the observed spectat

We report the case of a patient with mild haemophilia A, due to a Tyr2105Cys mutation in exon 22 of the C1 domain, who developed a high-titre factor VIII inhibitor (maximum titre 1600 BU) with recurrent severe haemorrhages and fatal intracranial bleeding. Based on published data, it appears that although this mutation occurs rarely in patients with mild or moderate haemophilia A, it is frequently

OBJECTIVE: Acute renal failure is common in septic patients. Fenoldopam, a dopamine-1 receptor agonist, increases renal blood flow and may, therefore, reduce the risk of acute renal failure in such patients. Accordingly, we sought to determine the safety and efficacy of fenoldopam for the prevention of acute renal failure in septic patients. DESIGN: Prospective, double-blind, placebo-controlled t

As corporations are going global, they are increasingly confronted with human rights challenges. As such, new ways to deal with human rights challenges in corporate operations must be developed as traditional governance mechanisms are not always able to tackle them. This article presents five different views on innovative solutions for the relationships between business and human rights that all b

According to IPCC reports, global climate change is likely to be accompanied by a greater frequency, intensity, and duration of heat waves in urban areas. This is related to predicted and ongoing variation of atmospheric temperature and its association with the dynamical evolution of cities. Changes in the roughness pattern of the surface, wind intensity, soil available humidity and radiative prop

Biochar produced in cookstoves has the potential to contribute to negative carbon emissions through sequestration of biomass carbon while also providing other benefits for sustainable development, including provision of clean renewable energy and increased yields in tropical agriculture. The aim of the reported research was to estimate effects on food production, household energy access and life c

Lignin is an abundant cell wall component, and it has been used mainly for generating steam and electricity. Nevertheless, lignin valorization, i.e. the conversion of lignin into high value-added fuels, chemicals, or materials, is crucial for the full implementation of cost-effective lignocellulosic biorefineries. From this perspective, rapid screening methods are crucial for time- and resource-ef

The formation of amyloid deposits in human tissues is a defining feature of more than 50 medical disorders, including Alzheimer’s disease. Strong genetic and histological evidence links these conditions to the process of protein aggregation, yet it has remained challenging to identify a definitive connection between aggregation and pathogenicity. Using time-resolved fluorescence microscopy of indi

Alzheimer's disease (AD) is a neurodegenerative disease which is manifested by a progressive and irreversible decline of cognition, memory loss, a shortened attention span, and changes in personality. Aging and genetic pre-dispositions, particularly the presence of a specific form of apolipoprotein E (APOE), are main risk factors of sporadic AD; however, a large body of evidence has shown that mul

Flooding is one of the main social impacts in urban areas, especially in larger, densely impermeable cities. Therefore, developing studies capable of identifying areas that are vulnerable to this type of event is crucial to provide early warning and a quick and effective response to reduce damages. Thus, this study sought to identify areas vulnerable to flood in the Igapó Lake Basin, a densely urb

Abstract: Patients with colorectal cancer may lack information about the disease and treatment. In 2017, a group consultation before start of surgery was introduced at a university hospital in western Sweden to inform about the disease, treatment, and ongoing scientific studies. The primary aim of this study was to explore the experience of the patients attending the group consultation. Based on s

Marfan syndrome (MFS) is a hereditary connective tissue disorder with an estimated prevalence of 1:5000–1:10 000 individuals. It is a pleiotropic disease characterized by specific ocular, cardiovascular, and skeletal features. The most common cardiovascular complication is aortic root dilatation which untreated can lead to life-threatening aortic root dissection, mainly occurring in adult patients

This short report is one of a series of outputs to flow from the international,interdisciplinary project ‘Looking back to move forwards: a social and cultural historyof home heating’ (JUSTHEAT), funded through the Collaboration of Humanities andSocial Sciences in Europe (CHANSE) initiative, which began in 2022 and runs until2025. Within this project, we aim to understand how major changes to home

In most clinical situations involving adenovirus infection, subgenus (subgroup) identification of an adenovirus isolate is as informative as a finer identification by serotype. A PCR method which allows the identification of human adenovirus isolates as members of subgenera A, B:1, B:2, C, D, E, or F is described. It is based on a simple (nonnested) PCR using primers which bind to regions immediat