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Sources and fates of dissolved organic carbon in lakes as determined by whole-lake carbon isotope additions

Four whole- lake inorganic C-13 addition experiments were conducted in lakes of differing trophic status. Inorganic C-13 addition enriched algal carbon in C-13 and changed the delta C-13- DOC by + 1.5 parts per thousand to + 9.5 parts per thousand, depending on the specific lake. This change in delta C-13- DOC represented a significant input of algal DOC that was not completely consumed by bacteri

Early onset of action and efficacy of a combination of calcipotriene and betamethasone dipropionate in the treatment of psoriasis

Background: Calcipotriene and betamethasone dipropionate are topical treatments for psoriasis vulgaris. Their mode of action is different. Improved risk/benefit may result with concomitant use of the two compounds together. A new vehicle has been created with the objective of obtaining optimal stability of both calcipotriene and betamethasone dipropionate in the combination product. Objective. We

A meta-analysis of prior corticosteroid use and fracture risk

The relationship between use of corticosteroids and fracture risk was estimated in a meta-analysis of data from seven cohort studies of similar to42,000 men and women. Current and past use of corticosteroids was an important predictor of fracture risk that was independent of prior fracture and BMD.

Radiation dose as a risk factor for malignant melanoma following childhood cancer

The aim of this study was to determine therapy-related risk factors for the development of melanoma after childhood cancer. Among 4401 3-year survivors of a childhood cancer in eight French and British centres and 25 120 patients younger than 20 years old at first malignant neoplasm (FMN) extracted from the Nordic Cancer Registries, 16 patients developed a melanoma as a second malignant neoplasm (

Geometrical information on core-excited states obtained from interference quenching of vibrational states in resonant x-ray photoemission

An interference quenching of the m=1 final state vibrational line in the resonant Auger decay of N 1s-->pi(*) core-excited N-2 is observed and analyzed. The intensity ratio between the m=1 and m=0 vibrational levels of the X (2)Sigma(g)(+) final state shows a surprising nonmonotonic variation as a function of frequency detuning, going through a minimum with a complete suppression of m=1. We have d

Dosimetric comparison of treatment planning systems in irradiation of breast with tangential fields

PURPOSE: The objectives of this study are: (1) to investigate the dosimetric differences of the different treatment planning systems (TPS) in breast irradiation with tangential fields, and (2) to study the effect of beam characteristics on dose distributions in tangential breast irradiation with 6 MV linear accelerators from different manufacturers. METHODS AND MATERIALS: Nine commercial and two u

Polyphasic identification of Bacillus and Brevibacillus strains from clinical, dairy and industrial specimens and proposal of Brevibacillus invocatus sp nov.

Thirty-three clinical, dairy and industrial isolates of aerobic endospore-forming bacteria which were unreactive in routine identification tests were characterized genotypically by using amplified rDNA restriction analysis (ARDRA), 16S rDNA sequencing and DNA-DNA reassociation, and phenotypically by using fatty acid methyll ester (FAME) analysis, SDS-PAGE of whole-cell proteins, API Biotype 100 as

Photon energy dependence of fragmentation of small argon clusters

Photofragmentation of small argon clusters with size below ten atoms is reported. In this size range significant modifications from the electronic properties and geometry take place. When tuning the photon energy through the argon 2p edge, the fragmentation pattern is changed. Specifically, cation dimer production is enhanced at the 2p(3/2)-> 4s resonance, while above the 2p edge almost complete a

The size of neutral free clusters as manifested in the relative bulk-to-surface intensity in core level photoelectron spectroscopy

A new approach for obtaining an estimate of the effective size of the free neutral clusters is proposed. The approach relies on an experimental measure of the surface and interior or "bulk" cluster atoms provided by the x-ray photoelectron spectroscopy and on a model for the attenuation of photoelectrons ejected from the bulk of the cluster as the result of the ionizing irradiation. The experiment

Comprehensive association testing of common mitochondrial DNA variation in metabolic disease

Many lines of evidence implicate mitochondria in phenotypic variation: ( a) rare mutations in mitochondrial proteins cause metabolic, neurological, and muscular disorders; ( b) alterations in oxidative phosphorylation are characteristic of type 2 diabetes, Parkinson disease, Huntington disease, and other diseases; and ( c) common missense variants in the mitochondrial genome ( mtDNA) have been imp

Angle-resolved photoion yield and resonant Auger spectroscopy for the doubly excited Rydberg states above the C 1s threshold of CO

Doubly excited core-hole states of carbon monoxide in the photon energy region of 300-305 eV, i.e., directly above the C 1s ionization threshold, have been studied using both angle-resolved ion-yield and high-resolution resonant Auger spectroscopies. The leading configurations of the most prominent doubly excited Rydberg states are assigned by careful analysis of the ion-yield spectra and the fina

No association between inhaled corticosteroids and whole body DXA in postmenopausal women.

Purpose Postmenopausal women treated with corticosteroids are regarded as a high-risk group due to the effect of both natural bone loss and possible adverse effects of treatment with inhaled corticosteroids (IC). Objective To compare bone mineral density (BMD) in postmenopausal women exposed only to IC (IC group, n = 106) with that of BMD in women not exposed to corticosteroids (n = 124) and women

High-resolution genomic profiles of breast cancer cell lines assessed by tiling BAC array comparative genomic hybridization.

A BAC-array platform for comparative genomic hybridization was constructed from a library of 32,433 clones providing complete genome coverage, and evaluated by screening for DNA copy number changes in 10 breast cancer cell lines (BT474, MCF7, HCC1937, SK-BR-3, L56Br-C1, ZR-75-1, JIMTI, MDA-MB-231, MDA-MB-361, and HCC2218) and one cell line derived from fibrocystic disease of the breast (MCF10A). T

Estimates of the prevalence and number of Fibromyalgia syndrome patients and their alpha-1 antitrypsin phenotypic distribution in ten countries

Objectives: During the last few years, clinical, epidemiological, and pathological evidence has suggested that inherited alpha-1 antitrypsin [AAT] deficiency might play a role in the development of the fibromyalgia syndrome [FMS], probably because of the loss of AAT anti-inflammatory efficacy. The objective of this study was to estimate the prevalence and number of FMS patients, and their AAT phen

Synchronization of a TDMA-OFDM frequency hopping system

We present a time division multiple access-orthogonal frequency division multiplexing (TDMA-OFDM)-based radio interface proposal for the Universal Mobile Telecommunication System (UMTS). We focus on synchronization and present an implementable algorithm for the tracking of the mobiles' time and frequency offsets at the base station in the uplink. This algorithm is based on estimation methods that

Actors, Institutions and Frames in Global Energy Politics

The global political economy of energy is marked by a fragmentation of actors, institutions and frames. The goal of this chapter is to map and critically interpret this fragmented landscape of energy governance. First, it provides a deconstruction of the global energy challenge, arguing that the world does not face a singular energy problem but in fact multiple energy-related challenges. Which ene

Learning outcomes of infants and young children with spinal muscular atrophy type I provided with modified-electric-toy-cars in their natural environment

Objectives: To examine powered mobility learning in children with spinal muscular atrophy (SMA) type I, involving families and evaluating goal attainment through the use of small, modified electric toy cars in the children’s natural environments. Design: Single-blind pilot intervention study derived from an originally planned wait-list randomized controlled trial. This report includes only the imm

The effect of treatment with bisoprolol-first versus enalapril-first on cardiac structure and function in heart failure

Background: In CIBIS III, initiating chronic heart failure (CHF) treatment with bisoprolol (target dose 10 mg q.d.) followed by combination therapy with enalapril (target dose 10 mg b.i.d.), compared to the opposite order, showed similar effects on survival and hospitalization. By echocardiography, we evaluated the effects of these treatment strategies on cardiac structure and function. Methods: I