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On properties of hydraulic equilibria in district heating networks

District heating networks are an integral part of the energy system in many countries. In future smart energy systems, they are expected to enhance energy flexibility and support the integration of renewable and waste energy sources. An important aspect of these networks is the control of flow rates, which dictates the heat delivered to consumers. This paper concerns the properties of flow rates i

Seeing, Scrolling, Engaging: A User-focused Study of Experience-based Valuation of Museum Content on Social Media.

Following the outbreak of new media technologies, researchers in museum studies have acknowledged the increasing importance of digital content creation for museums. Today, Social Media provides museums with the opportunity to engage with their audiences beyond museum walls and pursue their organizational mission in innovative ways. Despite a growing interest in the organizational changes that make

Testing a Coupled Shoreline and Beach-Dune Model for a Predictive Digital Twin of a Hybrid Dune-Dike System

In recent years, Predictive Digital Twins (PDT) have emerged as a potential tool to monitor and predict the behavior of dynamic systems, including nature-based solutions in natural coastal systems. Here, we test the potential of using a simple, coupled shoreline and beach-dune model as a base for a PDT. The models exchange sediment flux balance information at each time step and recalculate shoreli

Remote Sensing Based Pre-Season Yellow Rust Early Warning in Oromia, Ethiopia

Yellow rust (Puccinia striiformis f. sp. Tritici) is a crop disease caused by a fungus that regularly infects wheat and causes yield loss in Ethiopia. The disease has a significant impact on the country’s crop production, food security, health, and socioeconomic well-being. Anticipating yellow rust epidemics can help to better manage them and mitigate their adverse impacts. This study explores t

Automated motion analysis of bony joint structures from dynamic computer tomography images : A multi-atlas approach

Dynamic computer tomography (CT) is an emerging modality to analyze in-vivo joint kinematics at the bone level, but it requires manual bone segmentation and, in some instances, landmark identification. The objective of this study is to present an automated workflow for the assessment of three-dimensional in vivo joint kinematics from dynamic musculoskeletal CT images. The proposed method relies on

Digital Entry-Level Education in Physiotherapy : a Commentary to Inform Post-COVID-19 Future Directions

Currently, the coronavirus disease 2019 (COVID-19) severely influences physiotherapy education which is based mostly on face-to-face teaching. Thus, educators have been compelled to adapt their pedagogical approaches moving to digital education. In this commentary, we debate on digital education highlighting its effectiveness, the users’ perspectives, and its weakness in the context of physiothera

State of fairness in esfri projects

Since 2009 initiatives that were selected for the roadmap of the European Strategy Forum on Research Infrastructures started working to build research infrastructures for a wide range of research disciplines. An important result of the strategic discussions was that distributed infrastructure scenarios were now seen as “complex research facilities” in addition to, for example traditional centralis

A Case Study on Grassroots Environmentalism for Health and Sustainability in the Land of Fires (Italy)

This chapter provides a reassessment of the waste ‘crises’ in the so-called Land of Fires in Italy and highlights the contribution of local social mobilizations in advancing environmental justice and sustainability concerns. It is based on the long term collaboration between a social scientist and two activists, and it draws from a dialogue of academic and activist knowledge in the tradition of En

Massive glycation of protein HC, a low molecular weight lipocalin, in non-diabetic individuals

Human protein HC is a member of the lipocalin superfamily with unique properties since it carries a covalently bound fluorescent chromophore mediating the linkage of the major part of protein HC to several plasma proteins, with IgA as the dominating complex partner. Native protein HC displays characteristic absorption and fluorescence spectra similar to those of glycated proteins with advanced gly

Artificial gametes : perspectives of geneticists, ethicists and representatives of potential users

Several threads of research towards developing artificial gametes are ongoing in a number of research labs worldwide. The development of a technology that could generate gametes in vitro has significant potential for human reproduction, and raises a lot of interest, as evidenced by the frequent and extensive media coverage of research in this area. We have asked researchers involved in work with a

Evolution of conventional communication : A cross-cultural study of pantomimic re-enactments of transitive events

This study addresses the postulate of non-conventionality of pantomime, inherent in pantomimic scenarios of language origin. Since lack of semiotic conventions does not preclude micro-conventions resulting from cultural differences, pantomimes should be easier to interpret when the actor and recipient share the same culture than between two different cultures. In the study, Italian and Polish amat

Traffic engineering of multiple spanning tree routing networks: the load balancing case

This paper deals with optimal load balancing in telecommunication networks based on multiple spanning tree routing. This is the case in switched Ethernet networks where the operator configures different routing spanning trees and assigns each demand VLAN to one of the spanning trees. We consider modeling and solving three load balancing objectives: (i) minimization of the average link load with a

Oxidative metabolism of dopamine: a colour reaction from human midbrain analysed by mass spectrometry

In order to identify the protein responsible for a dopamine peroxidizing activity, previously described in human normal and parkinsonian substantia nigra by our group, we developed non-denaturing polyacrylamide gel electrophoresis conditions, mimicking the characteristic colour in vitro reaction, resulting from cyclic oxidation of dopamine (DA). After separating protein mixtures from human normal

Viremia during pregnancy and risk of childhood leukemia and lymphomas in the offspring: Nested case-control study.

A possible role for infections of the pregnant mother in the development of childhood acute leukemias and lymphomas has been suggested. However, no specific infectious agent has been identified. Offspring of 74,000 mothers who had serum samples taken during pregnancy and stored in a large-scale biobank were followed up to the age of 15 years (750,000 person years) through over-generation linkages

Images of the North : An imagological analysis of Nordic noir book covers in Greece and Spain

Although Scandinavia is arguably peripheral in the global literary system, it nevertheless holds a surprisingly prominent position in the field of translation, Swedish and Danish being among the ten most translated languages in the world (Lindqvist, 2015). What literature is selected for translation and introduction into new linguistic contexts is not a coincidence, but has to do with economic fac

Organic management and cover crop species steer soil microbial community structure and functionality along with soil organic matter properties

It is well recognized that organic soil management stimulates bacterial biomass and activity and that including cover crops in the rotation increases soil organic matter (SOM). Yet, to date the relative impact of different cover crop species and organic vs. non-organic soil management on soil bacteria and fungi and on SOM quantity and quality remains to be tested. We used a long-term (10 years) fu

The role of spatial texture in visual control of bumblebee learning flights

When leaving the nest for the first time, bees and wasps perform elaborate learning flights, during which the location of the nest is memorised. These flights are characterised by a succession of arcs or loops of increasing radius centred around the nest, with an incremental increase in ground speed, which requires precise control of the flight manoeuvres by the insect. Here, we investigated the r

Establishment of Melanoma Tumor Xenograft Using Single Cell Line Suspension and Co-injection of Patient-Derived T Cells in Immune-Deficient NSG Mice

When primary tumor cells are grown in vitro, they are exposed to an environment that is vastly different from the tumor environment they originate from. The in vitro environment can lack the three-dimensional structure of the tumor, other cell types present within the tumor microenvironment, and important growth factors. Humanized mouse models allow researchers to study primary tumor cells in a mo

A Deep View into the Nucleus of the Sagittarius Dwarf Spheroidal Galaxy with MUSE. II. Kinematic Characterization of the Stellar Populations

The Sagittarius dwarf spheroidal galaxy is in an advanced stage of disruption but still hosts its nuclear star cluster (NSC), M54, at its center. In this paper, we present a detailed kinematic characterization of the three stellar populations present in M54: Young metal-rich (YMR); intermediate-age metal-rich (IMR); and old metal-poor (OMP), based on the spectra of 6500 individual M54 member stars

Runaway and walkaway stars from the ONC with Gaia DR2

Theory predicts that we should find fast, ejected (runaway) stars of all masses around dense, young star-forming regions. N-body simulations show that the number and distribution of these ejected stars could be used to constrain the initial spatial and kinematic substructure of the regions. We search for runaway and slower walkaway stars within 100 pc of the Orion Nebula Cluster (ONC) using Gaia D