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Multiscale Reverse-Time-Migration-Type Imaging Using the Dyadic Parabolic Decomposition of Phase Space
We develop a representation of reverse-time migration (RTM) in terms of Fourier integral operators, the canonical relations of which are graphs. Through the dyadic parabolic decomposition of phase space, we obtain the solution of the wave equation with a boundary source and homogeneous initial conditions using wave packets. On this basis, we develop a numerical procedure for the reverse-time conti
Abundance structure and chemical evolution of the Galactic disc
Den anomiska rätten. Om undantagskonstruktionen av de rent ideella kränkningsersättningarna
Uppsatsen försöker att ta ett samlat rättssociologiskt grepp om kränkningsersättningen som är den viktigaste formen av brottsskadeersättning (under år 2006 betalade Brottsoffermyndighe-ten ut över 81 miljoner konor i kränkningsersättning). Hur dessa skador värderas och konstrueras speglar samhällets rättskultur och ger upphov till en rad rättssociologiska frågeställningar om rättens roll och samsp
Oxygenation of an anoxic fjord basin strongly stimulates benthic denitrification and DNRA
Hypoxia hampers eutrophication reduction efforts by enabling high nutrient fluxes from sediment to bottom waters. Oxygenation of hypoxic water bodies is often proposed to reduce benthic ammonium and phosphate release. This study investigates the functional response of benthic nitrate-reducing processes to a long-term engineered oxygenation effort in a density-stratified fjord with euxinic bottom w
Low wall stress in the popliteal artery: Other mechanisms responsible for the predilection of aneurysmal dilatation?
The popliteal artery (PA) is, after aorta, the most common site for aneurysm formation. Why the PA is more susceptible than other peripheral muscular arteries is unknown. We hypothesized that the wall composition, which in turn affects wall properties, as well as the circumferential wall stress (WS) imposed on the arterial wall, might differ compared to other muscular arteries. The aim was to stud
Differences between developed and developing countries in paediatric care in haemophilia
. The aim of this article is to provide an up-to-date overview on paediatric haemophilia care in the world, with emphasis on medical treatment, rehabilitation, and orthopaedic surgery. The reason these specific professions caregivers are included is that over 90% of bleeding episodes in people with haemophilia (PWH) occur within the musculoskeletal system; and of these 80% of bleedings occur in jo
Prevalence of knee pain and knee OA in southern Sweden and the proportion that seeks medical care.
The aim of this study was to estimate the prevalence of frequent knee pain in radiographic, symptomatic and clinically defined knee OA in middle-aged and elderly patients and the proportion that seeks medical care.
Novel gamma-carboxyglutamic acid-containing peptides from the venom of Conus textile
The cone snail is the only invertebrate system in which the vitamin K-dependent carboxylase (or gamma-carboxylase) and its product gamma-carboxyglutamic acid (Gla) have been identified. It remains the sole source of structural information of invertebrate gamma-carboxylase substrates. Four novel Gla-containing peptides were purified from the venom of Conus textile and characterized using biochemica
Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels.
Epigenetic variation may contribute to the development of complex metabolic diseases such as type 2 diabetes (T2D). Hepatic insulin resistance is a hallmark of T2D. However, it remains unknown if epigenetic alterations take place in the liver from diabetic subjects. Therefore, we investigated the genome-wide DNA methylation pattern in the liver from subjects with T2D and non-diabetic controls and
2D effects in laminar premixed flames stabilized on a flat flame burner
In the present work non-idealities of flat burner-stabilized flames at atmospheric and low pressures are examined using PIV measurements, which are supported by and analyzed with the help of CFD modeling. Radial and axial velocity profiles measured in the cold flow and in the flames at atmospheric and at lower pressures are presented. Two possible reasons for the drop in the apparent laminar burni
International variations in hip fracture probabilities: Implications for risk assessment
It is recommended that intervention thresholds should be based on absolute fracture risk, but there is a large variation in hip fracture incidence from different regions of the world. The aim of this study was to examine heterogeneity of hip fracture probability in different regions from recent estimates of hip fracture incidence and mortality to adjust intervention thresholds. Ten-year probabilit
A general approach to the apparent permeability index
The apparent permeability index is widely used as part of a general screening process to study drug absorption, and is routinely obtained from in vitro or ex vivo experiments. A classical example, widely used in the pharmaceutical industry, is the in vitro Caco-2 cell culture model. The index is defined as the initial flux of compound through the membrane (normalized by membrane surface area and d
Site-Selective Participator Decay of Core-Excited Butadiene
The decay of core-excited electronic states in free 1,3 trans butadiene molecules has been studied using high-resolution synchrotron radiation and electron spectrometry. The core-level energy shift between the terminal and central carbon atoms is 0.64 eV making selective excitation of core electrons from these atoms possible. Resonant excitation to the au(*) valence state leads to autoionizing dec
Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial
Background Postoperative policies of "wait-and-see" and radiotherapy for low-grade glioma are poorly defined. A trial in the mid 1980s established the radiation dose. In 1986 the EORTC Radiotherapy and Brain Tumor Groups initiated a prospective trial to compare early radiotherapy with delayed radiotherapy. An interim analysis has been reported. We now present the long-term results. Methods After s
Geminate charge recombination in alternating polyfluorene Copolymer/Fullerene blends
By measuring excited state and charge dynamics in blends of an alternating polyfluorene copolymer and fullerene derivative over nine orders in time and two orders in light intensity, we have monitored the light-induced processes from ultrafast charge photogeneration to much slower decay of charges by recombination. We find that at low light intensities relevant to solar cell operation relatively f
European curriculum for thrombosis and haemostasis.
Nanofiltration at elevated temperatures: Influence of the combined effects of temperature, salts, pH and cleaning
The influence of temperature, salts, pH, and various pre-treatments and cleaning on the nanofiltration (NF) performance of thin-film polyamide (PA) composite membranes has been investigated. The change in membrane performance was correlated to membrane swelling or/and electroviscous friction. Aspects of costs and energy demand while using NF at elevated temperatures were also evaluated. The increa
You never fake alone. Creative AI in action
Creative AI (notably GANs and VAEs) can generate convincing fakes of video footage, pictures, graphics, etc. In order to conceptualize the societal role of creative AI a new conceptual toolbox is needed. The paper provides metaphors and concepts for understanding the functioning of creative AI. It shows how the role of creative AI in relation to FAT ideals can be enriched by a dynamic and construc
Fatal outcome due to deficiency of subunit 6 of the conserved oligomeric Golgi complex leading to a new type of congenital disorders of glycosylation
Deficiency of subunit 6 of the conserved oligomeric Golgi (COG6) complex causes a new combined N-and O-glycosylation deficiency of the congenital disorders of glycosylation, designated as CDG-IIL (COG6-CDG). The index patient presented with a severe neurologic disease characterized by vitamin K deficiency, vomiting, intractable focal seizures, intracranial bleedings and fatal outcome in early infa
