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Recombinant production and characterization of six novel GH27 and GH36 α-galactosidases from Penicillium subrubescens and their synergism with a commercial mannanase during the hydrolysis of lignocellulosic biomass

α-Galactosidases are important industrial enzymes for hemicellulosic biomass degradation or modification. In this study, six novel extracellular α-galactosidases from Penicillium subrubescens were produced in Pichia pastoris and characterized. All α-galactosidases exhibited high affinity to pNPαGal, and only AglE was not active towards galacto-oligomers. Especially AglB and AglD released high amou

Hybrid zone analysis confirms cryptic species of banded newt and does not support competitive displacement since secondary contact

When two putatively cryptic species meet in nature, hybrid zone analysis can be used to estimate the extent of gene flow between them. Two recently recognized cryptic species of banded newt (genus Ommatotriton) are suspected to meet in parapatry in Anatolia, but a formal hybrid zone analysis has never been conducted. We sample populations throughout the range, with a focus on the supposed contact

SCIT-treatment With a Chemically Modified, Aluminum Hydroxide Adsorbed Peanut Extract (HAL-MPE1) Was Generally Safe And Well Tolerated And Showed Immunological Changes In Peanut Allergic Patients

RationaleThere is no effective disease modifying treatment for peanut allergy available. A Phase I safety and tolerability study was performed with a chemically modified, Al(OH)3 adsorbed peanut extract (HAL-MPE1) for subcutaneous immunotherapy (SCIT).MethodsIn a randomized, double-blind, placebo controlled, single-centre, Phase I study, 17 Caucasian subjects with peanut allergy were randomized to

Revised function analysis of sustainability : understanding the complexity of sustainability.

This article presents and discusses the case study “Scraping the surface,” aworkshop about sustainable design held for master’s students of different design majors at the FHNW Academy of Art and Design. Through marketing we, as consumers, are bombarded with products claiming to be sustainable. As a result, sustainability has become a buzz word. “Scraping the surface” highlighted the complex factor

Sensory modality profiles of antonyms

Adjectives that are used to describe sensory experiences are often used to express more than one modality. The adjective sweet, for instance, may primarily be associated with taste (i.e., taste is the dominant modality of sweet), but it can also be used for smell, sound or sight, and possibly even for touch. It has also been shown that some sensory modalities combine more easily than others. Many

Sustainable consumption and ecodesign : a review

Sustainable products have arrived on the market and faced competition with traditional products with one extra challenge: they normally tend to be more expensive than traditional ones. Customers are yet to pay more for these products as they are alerted for environmental impacts. However, the gap between knowledge and action is being decreased slowly. One of the factors for this sluggish behavior

Gender agreement in Italian compounds with capo-

Gender inflection for animated nouns in Italian presents challenges influenced by societal pressures and linguistic structure, especially in morphologically complex words like compounds. The study investigates gender inflection distribution in compounds with capo- compared to other nouns (i.e., occupations traditionally performed by women, by men, and the word capo in isolation), exploring the int

Bleeding phenotype according to factor level in 825 children with nonsevere hemophilia : data from the PedNet cohort

Background: Information on bleeding phenotype in nonsevere hemophilia may be used to determine target factor levels for prophylaxis or gene therapy in severe hemophilia. Objectives: To assess the association between endogenous factor level and bleeding phenotype in children with nonsevere (factor [F]VIII/FIX activity 1%-25%) hemophilia A (HA) and B without prophylaxis. Methods: Data on annualized

U-Pb geochronology of the Tsineng dyke swarm and paleomagnetism of the Hartley Basalt Formation, South Africa : evidence for two separate magmatic events at 1.93 – 1.92 and 1.88 – 1.84 Ga in the Kalahari craton

Geokronologi och paleomagnetiska studier är de viktigaste verktygen för paleogeografiska rekonstruktioner kring hur kontinenter fårhållit sig relativt till varandra under geologisk tid. Genom att jämföra s.k. polvandringskurvor och tidpunkter för storskaliga magmatiska händelser mellan olika krustala block (kontienter/kratoner) kan vi få en bättre förståelse av hur dessa block förhöll sig relativtRobust geochronology and well-constrained paleopoles are the main tools for paleogeographic reconstructions. Through the completion of so called barcode diagrams (matching of coeval events of mafic magmatism between blocks) and determination of the apparent polar wander paths, these studies provide a better understanding of the position of continents and supercontinents in the past. The robust U–P

Modeling the growth rates of potential forestry species in Rwanda: a tree structural traits-based approach

Forest plantations play a crucial role in the livelihoods of Rwandan people. They provide valuable wood resources, such as timber and biomass energy. The first plantations created in the colonial period from 1920 to 1948 contained only exotic Eucalyptus species, which is thought to out-perform native species in terms of more rapid wood production. Over time, this resulted in the domination of non-

Religionsfrihet i arbetslivet

Att ha en religion, tro eller övertygelse är en absolut mänsklig rättighet och får inte begränsas på något vis. Friheten att utöva sin religion eller övertygelse är också en skyddad rättighet, dock behöver den begränsas för att inte kränka andra individers friheter och rättigheter. I vilken utsträckning en arbetsgivare kan begränsa en arbetstagares religiösa uttryck på arbetsplatsen är ett omdebat

Bracing for the inevitable: An exploratory multi-case study of local climate change adaptation plans

Vulnerability to climate change and the capacity to adapt to it are the result of intersecting power structures, system dynamics, and social identity markers otherwise known as intersectionality; and thus, differ greatly between contexts. However, despite the stark contextual differences between small and metropolitan cities, and lower and higher income countries, the policy and study of climate c

The Right to be (Un)Seen - Means for Enactment of Human Rights in Situations of Encampment

The implementation of iris scan technology in the context of humanitarian financial assistance in UNHCR-run refugee camps raises an array of legal questions. While the collection and storage of biometrical data in other contexts is often accompanied by a critical discussion about data protection and privacy concerns, the use of such data in humanitarian settings is often left uncontested. The in-d

Dynamically predicted shelf-life label in minced meat product: A consumer-driven design and analysis

Dynamically predicted shelf-life label (DPSL) has been discussed to be one of the solutions to curb meat waste. Therefore, the research about the DPSL label and the perceptible information obtained by minced meat consumers is conducted. The research purpose is to identify the critical factors to design a DPSL label for minced meat consumers, and to design and assess the label with the consumers. T

Multiscale Reverse-Time-Migration-Type Imaging Using the Dyadic Parabolic Decomposition of Phase Space

We develop a representation of reverse-time migration (RTM) in terms of Fourier integral operators, the canonical relations of which are graphs. Through the dyadic parabolic decomposition of phase space, we obtain the solution of the wave equation with a boundary source and homogeneous initial conditions using wave packets. On this basis, we develop a numerical procedure for the reverse-time conti

Description of Telia's OFDM-based proposal

This document give an overview of Telias OFDM based proposal for UTRA and should be considered as an input to the OFDM concept group within SMG 2. The document describe the fundamental frame structure, principles of the detection, modulation, coding and synchronisation. Further on the channel structure, the resource management and handover principles are outlined.

A clinical study of efficacy and safety of the Carry Life UF system in continuous ambulatory peritoneal dialysis patients : protocol for a prospective, multicenter, randomized, crossover study

Background: Carry Life UF is a novel peritoneal dialysis (PD) technology for improved fluid management using steady concentration PD (SCPD). The Carry Life UF treatment starts with a manual peritoneal fill of 1.36% glucose PD fluid, followed by a 5-hour treatment where small amounts of glucose are continuously added to maintain a stable intraperitoneal glucose concentration. A recent in-center cli

Self-assembly of a hydrophobically modified naphthalene-labeled poly(acrylic acid) polyelectrolyte in water: Organic solvent mixtures followed by steady-state and time-resolved fluorescence

The solution properties of two water-soluble polymers, poly(acrylic acid) (PAA), covalently labeled with the fluorescent hydrophobic dye naphthalene (Np), have been investigated in water:organic solvent mixtures. The naphthalene chromophores have been randomly attached, onto the polymer, with two different degrees of labeling. Fluorescence measurements (steady-state and time-resolved) have been us