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. The aim of this article is to provide an up-to-date overview on paediatric haemophilia care in the world, with emphasis on medical treatment, rehabilitation, and orthopaedic surgery. The reason these specific professions caregivers are included is that over 90% of bleeding episodes in people with haemophilia (PWH) occur within the musculoskeletal system; and of these 80% of bleedings occur in jo
The aim of this study was to estimate the prevalence of frequent knee pain in radiographic, symptomatic and clinically defined knee OA in middle-aged and elderly patients and the proportion that seeks medical care.
Cinnamoyl-CoA reductase (CCR), an enzyme central to the lignin biosynthetic pathway, represents a promising biotechnological target to reduce lignin levels and to improve the commercial viability of lignocellulosic biomass. However, silencing of the CCR gene results in considerable flux changes of the general and monolignol-specific lignin pathways, ultimately leading to the accumulation of variou
Esta investigación analiza la feria agroecológica UNIMINUTO, un ejemplo destacado de economía solidaria y de consumo sostenible en Bogotá, Colombia. Al utilizar la teoría de las prácticas sociales y entrevistas semi-estructuradas con 10 consumidores frecuentes, este estudio identifica las principales motivaciones de los consumidores para asistir a este espacio, que incluyen el apoyo a los productoThis research examines the UNIMINUTO agroecological fair, a prominent example of solidarity economy and sustainable consumption in Bogotá, Colombia. Employing a social practice theory lens and semi-structured interviews with ten frequent attendees, this study identifies key consumer motivations, including support for local producers, product quality, health benefits, knowledge acquisition, and the
As climate change and unsustainable waste practices present major global challenges, effective waste management in developing countries becomes critically important. In South Africa, organic waste constitutes a significant share of general waste and is often landfilled, contributing to methane emissions and serious health risks for the population. In response, the Western Cape province has introdu
Active learning is increasingly implemented in higher education, yet students' perspectives on this pedagogical approach remain diverse. This study explores geoscience students' views on active learning within a course at the University of Bergen (UiB) and in relation to their broader study program. Through longitudinal qualitative interviews with two student cohorts, we identified seven main cate
Introduction: Falls among hospitalized older adults increase morbidity, prolong hospital stays, and raise healthcare costs. Sensor-based technologies and medical devices are emerging tools for fall prevention, but their clinical effectiveness remains uncertain. This systematic review aimed to assess their effectiveness in reducing inpatient falls, staff workload, and physical restraint use in hosp
This chapter delves into the evaluation of national innovation policies through a case study of the Brazilian National Innovation Policy (NIP). Assessing these policies poses several challenges, including the difficulty of defining and measuring policy outcomes, the scarcity of reliable data, and the intricacies of interactions among various stakeholders involved in the policy. Additionally, polit
A range of cardiovascular risk factors associated with stroke are known, but they do not explain all cases of stroke. Genetic factors can be responsible for certain forms of stroke, and are further investigated in this thesis. The aims of this thesis were to study the occurrence of familial clustering of stroke, compile known stroke-associated genetic conditions for diagnostic and research genetic
In this article, we analyze the nexus between political regimes and external voting rights. Using a global longitudinal dataset, we report that higher levels of inclusion and contestation bring higher probabilities that a state adopts and implements emigrant enfranchisement. Taking outliers from our quantitative assessment, we then further examine two liberal democracies, Ireland and Uruguay, and
In scenarios coined Maxwell's demon, information on microscopic degrees of freedom is used to seemingly violate the second law of thermodynamics. This has been studied in the classical as well as the quantum domain. In this paper, we study an implementation of Maxwell's demon that can operate in both domains. In particular, we investigate information-to-work conversion over the quantum-to-classica
The role of natural marine aerosols in the global climate system remains understudied and uncertain. This is true for the emissions of natural volatile compounds over the ocean, the oxidation of said compounds and their impact on particle formation and particle growth. In this thesis, the emission, chemistry and aerosol particle processes relating to these compounds were studied using different pr
A partial ichthyosaur skeleton from the Toarcian (Lower Jurassic) bituminous shales of the ‘Schistes Carton’ unit of southern Luxembourg is described and illustrated. In addition, associated remnant soft tissues are analyzed using a combination of imaging and molecular techniques. The fossil (MNHNL TV344) comprises scattered appendicular elements, together with a consecutive series of semi-articul
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It is generally recognized that large-scale whaling in the 19th and 20th century led to a substantial reduction of the size of many cetacean populations, particularly those of the baleen whales (Mysticeti). The impact of these operations on genomic diversity of one of the most hunted whales, the fin whale (Balaenoptera physalus), has remained largely unaddressed because of the paucity of adequate
Carbon emissions from buildings have inherently dynamic characteristics since buildings evolve over time. Most previous studies, however, implemented static building carbon regimes, ignoring the temporal variation of many factors that govern carbon emissions of buildings. This research explores the influences of four dynamic factors acting on building carbon emissions: dynamic climate change data,
This chapter takes an interest in the world of platforms for creative and cultural work. Platforms for creative and cultural work started to become popular in the late 20th century, and their popularity has grown rapidly over the years. Taking its point of departure from these platforms, this chapter aims to shed light upon and discuss the work of the professionals who handle and manage these platThis chapter takes an interest in the world of platforms for creative and cultural work. Platforms for creative and cultural work started to become popular in the late 20th century, and their popularity has grown rapidly over the years. Taking its point of departure from these platforms, this chapter aims to shed light upon and discuss the work of the professionals who handle and manage these plat
Municipal biowaste has a high potential for agricultural use. However, it requires an additional amendment to increase the nutritional content used during the composting process. The purpose of this study was to investigate the selection of compost-enhancing amendments from municipal biowaste using bibliometric and multicriteria analysis. The municipality of Yopal (Casanare, Colombia) was chosen a
