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The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. pyogenes infections, human plasma leaks into the site of infection as a consequence of infl
Cellular redox state is an important metabolic variable, influencing many aspects of cell function like growth, apoptosis, and reductive biosynthesis. In this report, we identify NADPH as a candidate signaling molecule for exocytosis in neuroendocrine cells. In pancreatic beta-cells, glucose acutely raised the NADPH-to-NADP(+) ratio and stimulated insulin release in parallel. Furthermore, intracel
Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei
NordIAS Visiting Fellowship Programme _____________ Call for Applications – 2026 Deadline 13 January 2026 The Nordic Institutes for Advanced Studies have formed the network NordIAS with the aim of increasing collaborations among the institutes and affiliated fellows and staff. The NordIAS visiting fellowship programme is intended to enhance the academic dialogue and network both for the fellows pa
https://www.pi.lu.se/sites/pi.lu.se/files/2025-11/NordIAS_Call-for-applications_2026.pdf - 2026-05-10
NordIAS Visiting Fellowship Programme, Call for Applications 2026 NordIAS Visiting Fellowship Programme _____________ Call for Applications – 2026 Deadline 13 January 2026 The Nordic Institutes for Advanced Studies have formed the network NordIAS with the aim of increasing collaborations among the institutes and affiliated fellows and staff. The NordIAS visiting fellowship programme is intended to
https://www.pi.lu.se/en/sites/pi.lu.se.en/files/2025-11/NordIAS_Call-for-applications_2026_0.pdf - 2026-05-10
Syftet med uppsatsen är att undersöka vad framgång är i dagens skandinaviska elitfotbollsklubbar och vilka strategier som är användbara för att uppnå denna. Uppsatsen ämnar således belysa och klargöra de viktigaste aspekterna i en lyckad strategi inom en modern skandinavisk fotbollsklubb. Med denna kunskap har vi för avsikt att återge en bild över hur en elitfotbollsklubb strategiskt bör organiser
Popular Abstract in Swedish Denna avhandling handlar om modeller för plana solfångare, transparent isolering och verkningsgradsfaktorer. En ekvation för energiutbytet från en glasad plan solfångare härleds genom att modellera verkningsgradsfaktorn, F´, som en summa av en konstant och en temperaturberoende del. Ett alternativt sätt att testa en plan solfångare, baserat på denna modell, föreslås. EThis thesis deals with models of flat plate collectors, transparent insulation and efficiency factors. An equation for the energy output from a glazed flat plate collector is derived by modelling the collector efficiency factor, F´ as the sum of a constant and a temperature dependent part. An alternative way of testing a flat plate collector, based on this model, is suggested. A complete set of a
A one-step HPLC method was developed for the purification of protein G, a cell wall molecule from group C and G streptococci with immunoglobulin G- and albumin-binding properties. Lysed Escherichia coli bacteria infected with lambda-phages containing the protein G gene from group G streptococci were used as a starting material for the preparations. The lysate was applied to a column with immobiliz
Glycoprotein B (gB, gpUL55) is a major antigen for the induction of neutralizing antibodies against human cytomegalovirus, making it an attractive antigen for active and passive immunoprophylaxis. The immunodominant region on gB is the antigenic domain 1 (AD-1), a complex structure which requires a minimal linear amino acid sequence of more than 75 amino acids (aa 552-635) for antibody binding. We
In this paper, the authors report the use of liquid-liquid partition chromatography (LLPC) in an aqueous polyethylene glycol (PEG)/dextran two-phase system to compare the surface properties (partition properties) of human antibodies and fragments thereof. The surface properties of all the monoclonal antibodies of different classes and subclasses investigated were within the same broad range as tha
To investigate the effects of a vitamin D3 analogue (BXL628) in a model of chronic cystitis, as calcitriol analogues might be an interesting new therapeutic option for interstitial cystitis, for although the cause of the disease remains unclear, the increase in mast cells in the mucosa and detrusor muscle are significant. We devised a mouse model of allergen-induced allergic cystitis that is assoc
Den förrädiska antikroppen Streptokocker är en lömsk bakterie som har många olika sätt att ta sig runt vårt immunförsvar. Den kan låtsas vara en del av vår kropp genom att klä sig själv i en proteinkapsel som är väldigt likt ett mänskligt protein, bryta ned våra celler med hjälp av utsöndrade gifter och använda vårt immunförsvar mot oss genom att binda antikroppar till sig själv. En virulensfaktoThe Group A streptococcus (GAS) (Streptococcus pyogenes) is a significant human pathogen known for causing a diverse range of diseases, spanning from mild diseases such as pharyngitis to life-threatening diseases such as necrotizing fasciitis. Its virulence comes from a plethora of immune evasion mechanisms, but the M protein with its hypervariable region and ability to bind human proteins, stands
The use of Islamic symbols in metal music has, until now, been a rare phenomenon. A few years ago, some black metal-bands in Istanbul started using Islamic symbols in both their artwork and lyrics, often in an anti-Islamic fashion. Although research on metal music is well established, little has been done on the relationship between black metal and Islam. This thesis explores the relationship betw
Foreign invested SMEs have recently become increasingly interested in China. The enterprises are in this report categorized as second wave companies since they follow the footsteps of previous pioneers, of which mostly were larger companies. The ambitions of the SMEs are either to sell products on the ever expanding Chinese market or to utilize the potential of low cost production for global marke
FRAF21 Franska: Grundkurs i Frankrike Semestre d’automne 2025 Hitta (student)boende i Toulouse Trouver un logement (étudiant) à Toulouse Detta dokument är tänkt som ett stöd för de studenter från Lunds universitet som kommer att åka till Université de Toulouse Jean Jaurès för att läsa franska under höstterminen 2025. Dokumentet innehåller information om hemsidor och länkar som hjälper er att komma
https://www.sol.lu.se/fileadmin/user_upload/sol/aemnen/sektion3/Logement_%C3%A9tudiant_%C3%A0_Toulouse_HT2025.docx - 2026-05-09
Tematiska samverkansinitiativ vid Lunds universitet European Environment Agency Myndigheten för tillgängliga medier Malmö universitetSigma Connectivity University of Wisconsin at Madison US Jonas Enebrand AB eFrid Kulturen i Lund Pensionsmyndigheten CR Competence AB WIN Water Pensionärernas riksförbund Riksarkivet Wrams-Gunnarstorp Gods AB Open University UK Skånes universitetssjukhus European Spa
InfraVis, a national research infrastructure for data visualization wishes to inform about their workshops that will help you make the best application possible. To better reach out with their research, researchers at all higher education institutions in Sweden are offered the opportunity to engage InfraVis for data visualization. This applies to all subject areas, from the humanities and social s
https://www.lusem.lu.se/internal/article/infravis-call-2025-opens-october - 2026-05-09
Is it possible to improve the antibodies that the body produces to fight SARS-CoV2? In a study led by researchers from Lund University in Sweden, this was investigated by redesigning antibodies and combining them against the virus. The modified antibodies have been tested in human cells and with mice. Many antibodies used to treat covid infection during the pandemic have been so-called neutralizin
https://www.medicine.lu.se/article/cocktail-modified-antibodies-provides-strong-effect-against-sars-cov-2 - 2026-05-09
