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When to Best Assess Breathlessness Abnormality During Incremental Cardiopulmonary Cycle Exercise Testing

Background: Breathlessness on exertion is a common, distressing, and limiting symptom that can be quantified on incremental cardiopulmonary exercise testing (CPET) using normative reference equations. Research Question: Is the breathlessness abnormality best uncovered and assessed at symptom limitation (peak exercise) compared with submaximal exercise intensities? Study Design and Methods: This wa

Supplemental oxygen for symptomatic relief in people with serious respiratory illness : a systematic review and meta-analysis

Background People with serious respiratory illness frequently have a high symptom burden and may be prescribed supplemental oxygen therapy with the aims of reducing the severity of breathlessness and improving health-related quality of life (HRQoL). This systematic review and meta-analysis aimed to assess the effectiveness of oxygen therapy versus no oxygen on 1) breathlessness, 2) HRQoL and 3) ad

Fall risk screening in older persons using a wearable sensor in free-living conditions – A pilot and feasibility study

Introduction: Wearable sensors measuring bodily movements used in free-living conditions may help predict falls in older persons. Assessing their use in this context is essential to identify potential challenges related to fall risk screening. Therefore, this study aimed to assess the feasibility of conducting a prospective study comparing self-rated and wearable sensor-based measures for the asse

Determinants and prognostic value of blood pressure trajectories during graded exercise

PURPOSE: The systolic blood pressure (SBP) response to exercise reflects cardiovascular health, with both exaggerated and blunted responses linked to adverse outcomes. Prior studies relied typically on peak SBP or two-point slopes for evaluation. We aimed to identify distinct SBP responses from full times-series recorded during maximal, graded exercise and assess their clinical determinants and pr

Modelling over-hygroscopic wood sorption isotherms based on quantitative wood anatomy

A sorption isotherm expresses the relation between ambient relative humidity (RH) and equilibrium moisture content of a material for a specific temperature. The sorption isotherm can generally be divided into a hygroscopic part covering low, medium and high RH levels, and an over-hygroscopic part close to 100% RH. For wood, the hygroscopic part is dominated by water uptake in cell walls and the ov

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The liberty of religion is not easy to define or regulate. It is closely connected to other liberties and rights. Starting from individual liberty, the consequence will be a right to religion or from religion, the right to change religion or confession, and the right to transition from religion to no religion, or from no religion to religion. It is obvious that the state, the religious denominatio

Using radio telemetry to study dispersal of the beetle Osmoderma eremita, an inhabitant of tree hollows

This paper describes a radio-tracking study of Osmoderma eremita, a large Scarabaeid beetle, living in hollow trees. The study seems to be the first in which radio telemetry has been used with a flying insect in the field. Some 74 adult beetles were tagged with radio transmitters weighing 0.48-0.52 1, and having a nominal battery life of 12-20 days. Transmissions were detected at ranges of up to 3

Antimicrobial resistance in urinary pathogens among Swedish nursing home residents remains low: a cross-sectional study comparing antimicrobial resistance from 2003 to 2012

Background: There are several risk factors for the colonisation, infection and spreading of antibiotic resistant bacteria among elderly residents of nursing homes. An updated estimate of the native prevalence of antimicrobial resistance in uropathogens among Swedish nursing home residents is needed. Methods: Urine specimens were collected for culture and antimicrobial susceptibility testing agains

Can enzymatic stoichiometry be used to determine growth-limiting nutrients for microorganisms? - A critical assessment in two subtropical soils

The measurement of potential enzymatic activities has been proposed as an efficient method to infer nutrient limitations for microorganisms in environmental samples. To validate this use, confirmation with direct methods of microbial growth responses to resource additions are required. We experimentally manipulated nutrient-poor soils from the afromontane subtropics with relatively low (grassland