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Comparing design processes for the BOP and TOP markets

The base (BOP) and the top (TOP) of the world income pyramid represent the poor people and the people from developed countries, respectively. About two-fifths of the world population can be categorized as poor. Poverty is a trap because children born to poor parents are likely to grow up to be poor adults. In recent years, a poverty reduction approach that combines business development with povert

Balancing innovation, 'ordre public' and morality in human germline editing : A call for more nuanced approaches in patent law

This chapter analyses the role that 'ordre public' and morality exceptions can play in the granting of patents on inventions in the field of human germline editing and the consequences of this policy option. In order to provide the context for such an analysis, the chapter will, first, provide an overview of the current patent landscape for relevant genome editing technologies, drawing attention t

Acoustophoresis enables the label-free separation of functionally different subsets of cultured bone marrow stromal cells

Culture-expanded mesenchymal stromal cells (MSCs) are promising candidates for clinical cell-based therapies. MSC products are heterogeneous and we therefore investigated whether acoustophoresis, an ultrasound-based separation technology, could be used for the label-free enrichment of functionally different MSC populations. Acoustophoresis uses an ultrasonic standing wave in a microchannel which d

Alpha-1-microglobulin protects from heme induced placenta and kidney damage in a pregnant ewe model for preeclampsia

INTRODUCTION: Previous gene expression analysis have identified fetal hemoglobin (HbF) as a plausible etiological factor in preeclampsia. Free hemoglobin and its degradation products, e.g. heme, are known to cause oxidative stress, tissue damage, and vaso-constriction, typical findings in preeclampsia.OBJECTIVE: To study alpha-1-microglobulin (A1M), an endogenous radical scavenger and heme-binder,

Luminance-Preserving and Temporally Stable Daltonization

We propose a novel, real-time algorithm for recoloring images to improve the experience for a color vision deficient observer. The output is temporally stable and preserves luminance, the most important visual cue. It runs in 0.2 ms per frame on a GPU.

Association of Prostate-Specific Antigen Levels with Prostate Cancer Risk in a Multiethnic Population : Stability over Time and Comparison with Polygenic Risk Score

BACKGROUND: Studies in men of European ancestry suggest prostate-specific antigen (PSA) as a marker of early prostate cancer (PCa) development that may help to risk-stratify men earlier in life.METHODS: We examined PSA levels in men measured up to 10+ years before a PCa diagnosis in association with PCa risk in 2,245 cases and 2,203 controls of African American, Latino, Japanese, Native Hawaiian,

Är kommunernas avkastning från dess bostadsaktiebolag marknadsmässig? - En kartläggning och jämförelse över perioden 2011–2018

De kommunala bostadsaktiebolagen, tillsammans med vissa stiftelser, är vad som utgör Sveriges allmännytta och är ett av kommunernas viktigaste verktyg för att främja bostadsmarknaden. Allmännyttan regleras av lagen (SFS 2010:879) om allmännyttiga kommunala bostadsaktiebolag, förkortad Allbolagen. Bolagen ska i allmännyttigt syfte främja bostadsförsörjningen i kommunen genom att erbjuda goda hyresbReal estate companies owned by Swedish municipalities, together with certain foundations, constitute what we call Allmännyttan. Allmännyttan is one of our municipalities’ most important tools for promoting public housing and is regulated by the law, abbreviated Allbolagen (SFS 2010:879). For purposes of public benefits, the municipal real estate companies are obliged to promote housing supply in t

Nordic and Baltic Case Studies and Assessments in Enterprises - CREDIT Report 2

This report summarizes 28 case studies addressing the common interest for indicators in case studies in Nordic and Baltic countries and is distributed to different building types – Benchmarking systems and indicators (4 case studies) – Offices (7 case studies) – Housing (8 case studies) – School and nursery (5 case studies) – Shopping centres (3 case studies) – Hospital (1 case studies) There are

Man skall inte skjuta sparvar med kanoner - En analys av den unionsrättsliga proportionalitetsbedömningen på den direkta beskattningens område

Ett medlemskap i EU innebär långtgående rättsliga konsekvenser på nationell nivå. Medlemsstaternas suveränitet är emellertid fortfarande relativt oinskränkt på den direkta beskattningens område, vilket följer av att unionen saknar befogenhet på området och medlemsstaterna således åtnjuter exklusiv kompentens. Medlemsstaterna kan fritt utforma sina skattesystem, men den nationella beskattningsrätteAn EU accession involves far-reaching legal consequences on a national level. Nevertheless, the sovereignty of the member states has remained relatively unrestricted in the area of direct taxation. The Union has no remit of competence in the area and the Member States therefore enjoy exclusive competence when it comes to direct taxation. The Member states maintain the right to design their own tax

Att bli förälder på förbjuden väg - en kvalitativ studie om frivilligt ensamstående mödrar som skaffar barn genom assisterad befruktning i Sverige

Author: Lovisa Ottoson & Lykke Olsson Title: To become a parent in a forbidden way - a qualitative study on single mothers by choice in Sweden who have children through assisted reproduction Supervisor: Roberto Scaramuzzino Assessor: Frans Oddner The purpose of this study is to examine how single mothers by choice experience that norms in our society affects them. It is interesting to see how

The application of Article 82 EC to tie-in agreements

Abusive behaviour by dominant undertakings is regulated in Article 82 EC. One of the ways to abuse a dominant position is through tying or bundling, and Article 82(d) states that: ''making the conclusion of contracts subject to acceptance by the other parties of supplementary obligations which, by their nature or according to commercial usage, have no connection with the subject of such co

Geographies of fear – visitors’ perceptions of safety in urban destinations

Countering fear and promoting experiences of security and safety among visitors are key issues in creating socially sustainable urban destinations. Security branding is a growing place branding paradigm through which to enhance experiences and perceptions of safety in cities, nations and regions (Coaffee and Van Ham, 2008; Coaffee and Rogers, 2008; Avraham and Ketter, 2008). This paper discusses h

Healthy workplaces for women and men of all ages

The aim of this knowledge compilation is to contribute with know-ledge about the work environment in relation to the ever-older workforce. How do employee needs and possibilities change from a course of life perspective? What should the employer and other work environment actors think about in order for the workforce to be able to and want to work to a high age? The Swedish Work Environment Author

“Toxic, but in a good way” : H&M in Russia during the Ukraine war as seen through consumer activism on TikTok

While scholars have explored how business has increasingly been involved in socio-political issues (Scherer et al., 2016; van der Meer & Jonkman, 2021), less attention has been given to the process of how businesses are held accountable for those issues by stakeholders (Reinecke & Ansari, 2016). Current studies show that multinational corporations are sometimes forced to take a stand on di

Hur ska stommar se ut för effektiv demontering och vilka hinder och utvecklingspotential ser stomentreprenörer och fastighetsbolag?

Bygg- och fastighetsbranschen utgör i dagsläget en betydande andel av Sveriges naturresursutvinning samt klimatpåverkan, där påverkan från traditionella stommar av betong och stål länge har dominerat. Klimatintensiva processer såsom cement- och stålproduktion är bidragande faktorer till att branschen är i behov av en hållbar och cirkulär omställning. Återbruk och cirkulärt byggande erbjuder hållbaToday, the construction and real estate industry accounts for a sizable portion of the market´s material consumption and climate impact, with traditional structural materials such as concrete and steel long dominated. Processes such as cement and steel production contribute to the industry´s need for a sustainable transition and circular transition. Reuse and circular construction offer sustainabl

Anxiety and depression impact exertional breathlessness in daily life and during exercise testing : the CanCOLD study

Background Exertional breathlessness is a limiting symptom that often coexists with anxiety and depression. We tested the hypothesis that anxiety and depression negatively impact exertional breathlessness in daily life and during standardised cardiopulmonary exercise testing (CPET). Methods Analysis of people aged ⩾40 years undergoing incremental cycle CPET. Exertional breathlessness in daily life