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Effects of Dietary Fibre and Probiotics on Hindgut Fermentation in Healthy Rats and in Rats with Dextran Sulphate Sodium-Induced Colitis and Colon Cancer

The importance of colonic fermentation has been realised during recent years as it has been found to be associated with colonic health and thus the overall health of the individual. The fermentation of dietary fibre and the addition of probiotics can have positive effects on the luminal environment and the colonic microbiota. Short-chain fatty acids, formed by the fermentation of dietary fibre, ha

Tracking environmental changes of the Baltic Sea coastal zone since mid-Holocene

Popular Abstract in Swedish I min avhandling har jag studerat marina sedimentkärnor från två kustområden i SE Sverige, dels från Gåsfjärden, strax söder om Västervik i Småland, och dels från kusten utanför Karlskrona i Blekinge. Med syftet att studera hur Östersjöns kustmiljö har förändrats sedan mitten av Holocen (~5000 år sedan). Resultaten visar att kustmiljön har påverkats av flera stressfaktoIn this thesis, I used two coastal sediment sequences from SE Sweden to study how Baltic Sea coastal environment has changed since the mid-Holocene. The results show the coastal environment has been influenced by multi-stressors, such as climate change, shoreline regression and anthropogenic activities. Using the sediment sequence from Karlskrona Bay, past coastal environment between 7300 and 350

Enzymatic synthesis of acrylates. Catalyst properties and development of process and product

The increasingly apparent environmental problems in our surroundings necessitate a quest for sustainable development in all areas of human endeavour. Within the field of chemistry and the production of chemicals, the focus is increasingly on the development of green chemistry. This discipline aims to reduce environmental impact by replacing petrochemical raw materials with renewable feedstock and

Managing Uncertainty in Environmental and Cost Life Cycle Studies of Building Design

Byggnadssektorn stod för 39 % av energi- och processrelaterade koldioxidutsläpp år 2018 och globala utsläpp från byggnader ökade med 2 % för det andra året i rad. Därför är det viktigt att ta fram lösningar på byggnadsdesign som minimerar klimatpåverkan från byggnader. Samtidigt som produktionen av bostäder och kommersiella byggnader måste vara kostnadseffektiv för att skapa boende och arbetsplatsThe building and construction sector accounted for 39% of energy and process-related carbon dioxide emissions in 2018 and global emissions from buildings increased by 2% for the second consecutive year. It is therefore important to find building design solutions that minimise the climate impact of buildings. At the same time, the production of residential houses and commercial buildings must be co

Efficacy of once-daily, high-dose, oral insulin immunotherapy in children genetically at risk for type 1 diabetes (POInT): a European, randomised, placebo-controlled, primary prevention trial

Background Type 1 diabetes begins with autoimmunity against pancreatic islet antigens, including insulin. The aim of the Primary Oral Insulin Trial (POInT) was to evaluate the efficacy and safety of daily high-dose oral insulin to prevent the development of islet autoantibodies and diabetes. Methods In this randomised, controlled, primary prevention trial, genetic screening in seven obstetric and

Microbial and enzymatic syntheses of polymer building blocks through selective transformations of polyols and furans

AbstractTransition from fossil- to bio-based economy is a critical step towards reduction of greenhouse gas emissions and climate change, and hence for achievement of sustainable communities and environment. In order to be fossil-free, the chemical and material industry is in need of carbon-neutral building blocks from renewable resources for the diverse array of products that are currently produc

Quality of life in patients with recurrent ovarian cancer treated with niraparib versus placebo (ENGOT-OV16/NOVA) : results from a double-blind, phase 3, randomised controlled trial

Background: Quality of life (QOL) has become an important complementary endpoint in cancer clinical studies alongside more traditional assessments (eg, tumour response, progression-free survival, overall survival). Niraparib maintenance treatment has been shown to significantly improve progression-free survival in patients with recurrent ovarian cancer. We aimed to assess whether the benefits of e

Statistical Modeling and Learning of the Environmental and Genetic Drivers of Variation in Human Immunity

During the last decade the variation in the human genome has been mapped in fine detail. Next generation sequencing has made it possible to cheaply and rapidly aquire vast amounts of biomolecular information on large cohorts of people. This have enabled large-scale epidemiological studies to investigate the relationships between environmental and genetic factors and human biomolecular traits. It i

Leisure in Late Capitalism

There is no apparent need for individuals to endure this kind of suffering in contemporary Western society with all its advantages. Nevertheless, endurance running is now a mainstream leisure pursuit. Why do hundreds of thousands of men, women and even children choose this torturous kind of leisure activity?In previous literature on consumption of extraordinary experiences, authors focus on the pu

Advances in time–domain induced polarisation tomography : Data acquisition, processing and modelling

Vad står vi på – hur tar man reda på det? Kanske man kan titta på en geologisk karta, borra ett hål eller gräva en grop? Det kan gå bra, men ibland finns det inte tillräckligt detaljerade kartor och att gräva upp allt man är intresserad av är ingen lysande idé. Tänk om man kunde forska fram en metod som gör att man kan se rakt igenom marken, som röntgenundersökningar på sjukhus! På sätt och vis kaWhat would you find below your feet – how do you find out? Perhaps you could look at a geological map, drill, or dig? That could work, but sometimes the maps are not detailed enough, and digging everywhere to find out is impractical. Imagine if you could develop a method that allows you to see straight through the ground, as x–rays through the body! To some extent, such methods already exist; you

Near-real-time CO2 fluxes from CarbonTracker Europe for high-resolution atmospheric modeling

We present the CarbonTracker Europe High-Resolution (CTE-HR) system that estimates carbon dioxide (CO2) exchange over Europe at high resolution (0.1 × 0.2° ) and in near real time (about 2 months' latency). It includes a dynamic anthropogenic emission model, which uses easily available statistics on economic activity, energy use, and weather to generate anthropogenic emissions with dynamic time pr

How to Bridge the Gap between Contracted Sourcing Net Savings and Actual Realized Savings

Background Many companies today spend more than half of their sales turnover on purchased parts and services. One dollar saved in purchasing costs contributes straight to the bottom line of the company in theory. Besides from accounting, sourcing and purchasing activities contribute to risk management and value improvement. (Van Weele, 2014) Still, many practical challenges of implementing balance

Sludge biochar as an adsorbent for pharmaceutical residues in wastewater

Den svenska avloppsvattenreningsprocessen består av flera olika steg som utnyttjar mekanisk, kemisk och biologisk rening för att avlägsna så mycket av ohälsosamma ämnen och organismer som möjligt från vattenomloppet. Avloppsvattenreningsprocesserna i Sverige saknar specifika reningsmetoder för vissa typer av organiskt material, såsom läkemedelsrester. Dessa mikroföroreningar bryts enbart delvis neThe Swedish wastewater treatment processes consists of multiple steps including mechanical, chemical, and biological cleaning to remove as much of the unhealthy substances and organisms as possible from the water circulation. The wastewater treatment process in Sweden lacks specific removal methods for some types of organic material, such as pharmaceutical residues and other microcontaminants. The

Exploatering av förorenade fastigheter - En studie av fördelning av ansvar, kostnader och risk

Centrala lägen av städerna vilka tidigare nyttjats för industri har genom ett förändrande samhälle och ekonomi kommit att lämnats orörda och i förfall. Detta medför att det idag finns attraktiva fastigheter med potentiella föroreningar i mark och byggnader vilka samhället nu önskar utnyttja för andra ändamål såsom bostäder, kontor och handel. Exploatering av dessa områden innebär stora kostnader oAttractive locations in cities, previously used for industry, have been left untouched and in disrepair due to changes in society and the economy. This situation has resulted in central properties with potentially contaminated land and buildings that society now wishes to redevelop for housing, offices and commerce. Developing these areas involves significant costs and uncertainties for potential

Den digitala handelns fastighetsmarknad - Var ska E-handeln lokaliseras?

Att E-handeln ökat stort de senaste åren har inte gått ouppmärksammat och dess inslag har märkts både privat och inom näringslivet. Den fysiska handeln har ändrats handel via internet vilket är en utveckling från byteshandel som var en av de tidigaste handelsformerna. Sedan internet, och E-handelns, lansering i början av 1990-talet har utvecklingen gått snabbt och de senaste tjugo åren har omsättnThe fact that e-commerce has increased significantly in recent years has not gone unnoticed, and its features have been marked in both private life as well as in business. The physical commerce has changed to an increased shopping through the internet, which is a development of the trade of goods that was one of the earliest commercial forms. Since the internet, and thereby the E-commerce, was lau

Förtätningsmöjligheter längs Kontinentalbanan i Malmö - En förstudie av förtätningspotentialen för två stationsnära områden

Malmö stad har i sin översiktsplan från 2018 fastlagt att utbyggnad ska ske som förtätning innanför Yttre Ringvägen. Vidare prioriteras enligt planen förtätning i stationsnära lägen. Därutöver återöppnades den gamla Kontinentalbanan i Malmö, i december 2018. Längs med denna järnväg syns områden som i linje med den översiktliga planeringen skulle kunna ha förutsättningar för förtätning. Med grund iThe city of Malmo has in its comprehensive plan from 2018 determined that further urban development should be planned in the ways of urban densification, within the border created by the outer main ring road of Malmo. According to the plan, urban densification within proximity to any commuting station will be prioritized. Besides that, there was a railway in Malmo named Kontinentalbanan that reope

Using GeoTools to Implement the Multi -Criteria Evaluation Analysis : Weighted Linear Combination Model

Multi-Criteria Evaluation Analysis (MCEA) is a decision making method employed to solve optimization problems that require the evaluation of a set of criteria to build an optimal decision. Where MCEA is integrated with GIS, optimization problems with spatial aspects, such as finding the best location of a facility across an area, could be solved. MCEA is implemented through different criteria dec

Solceller på Sysavs återvinningscentraler och avfallsanläggningar – en undersökning av potentialen för produktion av solel

Dagens samhälle håller på att elektrifieras och mer förnybar energi behövs, speciellt i södra Sverige där förbrukningen av el är betydligt högre än produktionen. Även elpriserna håller på att förändras och är just nu på väldigt höga nivåer. Sysav är ett avfallsaktiebolag i Skåne med 16 anläggningar, däribland soptippar även kallade deponiner. Sysav vill bidra till den förnybara energiproduktionen Todays society is moving towards electrification. This means that more renewable energy is needed. In the southern parts of Sweden the energy consumption is far greater than the production and the electricity prices are rising. Sysav is a company that takes care of the waste and recycling. They have 16 facilities in the south of Skåne, including landfills. Sysav has a vision to contribute to the r

The implications of the Kyoto agreement - the background and effects on the Puld Industry

Climate change is considered to be among the most serious threats to the sustainability of the world's environment, the health and well being of its people and the global economy. The rising levels of greenhouse gases in the global atmosphere are expected to cause a rise in global temperatures. In Kyoto, December 1997, the Kyoto Protocol was written under which industrialised countries have ad

Schenker's Box Handling Processes for Dell Computers at a Cross-Docking Centre in Copenhagen.

The 17th September 2001 the distributor Schenker started to cooperate with the computer systems manufacturer Dell to deliver Dell's products to the Nordic market. In the beginning of a new cooperation new processes are formed and they are often developed to solve the local, immediate problems without considering the overall picture. In the distribution network from Dell's plants in Ire