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Tubulointerstitial nephritis is a common cause of kidney failure and may have diverse etiologies. This form of nephritis is sometimes associated with autoimmune disease, but the role of autoimmune mechanisms in disease development is not well understood. Here, we present the cases of three patients with autoimmune polyendocrine syndrome type 1 who developed tubulointerstitial nephritis and ESRD in
Autoantibodies against a constituent of the glomerular basement membrane (GBM), the α3-chain of type IV collagen, can cause both rapidly progressive glomerulonephritis and alveolar hemorrhage, referred to as anti-GBM disease or Goodpasture disease. Anti-GBM antibodies generally are of immunoglobulin G subclass 1 (IgG1) and can in most cases readily be detected in the circulation using enzyme-linke
Ficolins are soluble molecules that bind carbohydrate present on the surface of microorganisms and function as recognition molecules in the lectin complement pathway. Three ficolins have been identified in humans: ficolin-1, ficolin-2, and ficolin-3. Ficolin-1 is synthesized in monocytes and type II alveolar epithelial cells. Ficolin-1 has been shown to be present in secretory granules of human ne
Arbetet med avslutande rapport har genomförts på uppdrag av en myndighet. Kvalitetssäkringen består i att ett omfattande, på myndigheten internt, utbildningsunderlag vetenskapligt förankrats genom en "process tracing". Resultatet medför en kvalitativt säkrare och mer robust utbildning, och ligger till grund för den framtida utvecklingen av ämnet.
This article focuses on production and reception practices for live reality television, using critical theory and empirical research to question how producers and audiences co-create and limit live experiences. The concept of care structures is used to make visible hidden labour in the creation of mood, in particular audiences as participants in the management of live experiences. In the case of G
Media audiences and reception studies is a shifting area of research in terms of theories and concepts, methodologies and methods. Audiences are on the move, and ways of understanding these transitions involves multi-faceted, pragmatic approaches to varieties of audience experiences in context, including contexts of distribution and media flows, genres and communicative form, and identities and ev
Since 1979, every municipality in Sweden has been able to offerits inhabitants Special Transportation Service (STS). STS has afirm primary-municipality connection and organization. Themunicipality, however, receives a national subsidy, which todayamounts to a maximum of 35 percent of a municipality'soverall costs for STS. In 1986, 5 percent of the Swedish populationwas entitled to Special Transpor
In a mail survey of about 900 men and women above the age of 65 living in one small and large city in Sweden and also in a longitudinal and cohort comparison population study of people between the ages of 70 to 79, living in another large city, questions were asked about car-driving and the possession of a driver's license and of a car. In the age-group 65-74 half of the households owned a car, wh
Many people are living with the consequences of a stroke for a great partof their lives, but knowledge is lacking on how rehabilitation and social services should bedesigned in a long-term perspective. There is a particular need for knowledge on how tosupport long-term participation in social and leisure activities.
