Search results

A machine allowing researchers to rely on objective, automatized readouts instead of subjective manual counting under the microscope. Incredible pictures. And the possibility to follow live cellular events. The Operetta is the answer to these demands. The interest in using the new MultiPark infrastructure is big. In March, MultiPark received the new Operetta CLS instrument, upgrading the former Ce

https://www.multipark.lu.se/article/seven-tones-operetta-multiparks-new-high-content-analysis-platform - 2026-05-09

Our research We study neurological diseases at the intersection between clinical research, biochemistry, and computer science. A key topic in our work is Alzheimer’s disease, where we study large patient cohorts using biochemistry, cell models, genetic analyses, advanced neuroimaging, and cognitive tests. To optimally use this multimodal data, we use state-of-the-art machine learning and artificia

https://www.multipark.lu.se/computational-neurology - 2026-05-09

Our research We study frontotemporal dementia, the second most common neurodegenerative dementing disorder. Our focus is twofold: improving the diagnostic process through the use of biomarkers (PET and fluid biomarkers), and increased understanding of the disease mechanisms, mainly using MRI. Also, we participate in the development of international guidelines for the diagnosis and management of th

https://www.multipark.lu.se/frontotemporal-dementia-research-unit - 2026-05-09

Our research My team focuses on developing accurate methods for early diagnosis of Alzheimer's and Parkinson's disease related disorders. We also aim to unravel the interplay between different pathologic events in humans with pre-symptomatic or prodromal disease, as well as to investigate different subtypes of the diseases.  Finally, we are focusing on improving clinical trials evaluating new dise

https://www.multipark.lu.se/clinical-memory-research-unit - 2026-05-09

Our research We are interested in how gene expression is regulated in the brain and how this process influences human brain evolution, neurodegenerative diseases, psychiatric disorders, and brain tumors. Our current focus is to study the role of epigenetic mechanisms and transposable elements. Our technical expertise includes CRISPR, reprogramming, bioinformatics, single-cell analysis, and human s

https://www.multipark.lu.se/laboratory-molecular-neurogenetics - 2026-05-09

Our DNA is very similar to that of the chimpanzee, which in evolutionary terms is our closest living relative. Stem cell researchers at Lund University in Sweden have now found a previously overlooked part of our DNA, so-called non-coded DNA, that appears to contribute to a difference which, despite all our similarities, may explain why our brains work differently. The study is published in the jo

https://www.multipark.lu.se/article/what-makes-us-human-answer-may-be-found-overlooked-dna - 2026-05-09

During her thesis project, Nadja Gustavsson has characterized structural changes inside neurons of a new mouse model for mixed neurogenerative disorders. On the 21st of October, she is defending her thesis supervised by Oxana Klementieva. In this interview, Nadja shares her ups and downs during her time as a Ph.D. student in MultiPark. Tell us about your Ph.D. research! Our lab utilizes a novel ap

https://www.multipark.lu.se/article/phd-defence-interview-nadja-gustavsson - 2026-05-09

Our research Our main focus is understanding peripheral pathology in Huntington’s disease (HD) and to investigate its importance for disease pathogenesis and biomarkers. HD is the most common inherited neurodegenerative disorder and is often regarded as a model for both sporadic and inherited neurodegenerative diseases. Many clinical features of HD can be ascribed to the dysfunction and death of n

https://www.multipark.lu.se/brain-disease-biomarker-unit - 2026-05-09

Our researchOur research focuses on identifying new early mechanisms and biomarkers associated with Alzheimer's disease (AD) and thereby improve the development of new treatments and diagnostic tools. Our strategy is to investigate the effect of AD risk factors like stress, inflammation, metabolic changes, and amyloidogenesis, on different types of brain cells including pericytes, astrocytes, neur

https://www.multipark.lu.se/cognitive-disorder-research-unit - 2026-05-09

Our research Motor impairments are common among people with neurodegenerative diseases such as Parkinson’s disease (PD). In older people in general, some motor abilities seem to decline prior to the development of a major neurocognitive disorder, i.e. dementia. Our research primarily involves patients with PD and those at risk of developing dementia. We address health from a broad perspective, inc

https://www.multipark.lu.se/rehabmotor-aspects - 2026-05-09

Meningitis is a very serious brain infection with limited treatment options. In a new study performed in rats, researchers from the University of Copenhagen present an alternative treatment based on immune cells that helps rinse away toxins that accumulate during the infection. Fever, headache, confusion, seizures, amputations, or death. Meningitis is a very serious brain infection that can affect

https://www.multipark.lu.se/article/meningitis-researchers-find-possible-treatment-strategy-without-antibiotics - 2026-05-09

Collaboration, networking, career development, and wellbeing. Those are four examples of needs that the newly formed young MultiParkers working group will address. After organizing their first event, they are eager to start preparing for more events. During the pandemic, there has been an upbuild of need for social gathering and exchange of ideas and experiences. Especially young researchers who r

https://www.multipark.lu.se/article/young-multiparkers-working-group-takes-shape - 2026-05-09

Receiving grants from the Swedish Research Council is viewed as a quality mark and one of the critical steps for young scientists to establish an independent research group. Last week, nine of MultiPark’s research leaders were awarded 31.6 million SEK for their projects. This year’s support from the Swedish Research Council encouraged MultiPark’s ambition to be a multidisciplinary research area. P

https://www.multipark.lu.se/article/nine-multipark-scientists-granted-support-swedish-research-council - 2026-05-09

During his research education, Jonathan Timpka wanted to elucidate what is affecting the ability to work for patients diagnosed with Parkinson’s disease. Defending his Ph.D. thesis on November 19th, Jonathan tells about his wide range of projects within the Restorative Parkinson Unit led by Per Odin. Tell us about your Ph.D. research! My research engagement has been quite diverse, ranging from reg

https://www.multipark.lu.se/article/phd-defence-interview-jonathan-timpka - 2026-05-09

Flow Cytometry Analysis and Fluorecence Activated Cell Sorting (FACS) Flow cytometry enables measurement of fluorescence intensity of particles (cells) in a liquid stream. Analysis of live and fixed cells may be based on size, granularity/complexity, fluorescent proteins, cell surface antigen expression, intracellular antigen expression, DNA content. Flow cytometry is ideal for multiplexing target

https://www.multipark.lu.se/infrastructures/facs-platform - 2026-05-09

Gene expression inside Parkinson’s disease patient’s brain cells seems to trigger structural changes of the Parkinson-linked protein alpha-synuclein. This was discovered when MultiPark researchers converted skin cells from Parkinson patients into midbrain cells in the dish. The study was published in Acta Neuropathologica Communications. Parkinson’s disease (PD) is a neurodegenerative disorder lin

https://www.multipark.lu.se/article/environment-inside-brain-cells-holds-clues-protein-aggregation - 2026-05-09

Emil Ygland Rödström is defending his thesis on the 20th of November. His research is about clinical, genetical, and biochemical biomarkers for the prognosis of Parkinson’s disease patients. Here, he tells us more about the discoveries and his time as a Ph.D. student in the Clinical Neurogenetics group at MultiPark. What is your research about? My thesis work consists of two different parts. In th

https://www.multipark.lu.se/article/phd-defence-interview-emil-ygland - 2026-05-09

Presently many of Sweden’s 20,000 Parkinson’s patients are not receiving the treatment they need, and many of the most seriously ill receive incorrect or inappropriate therapy. With the new Manage PD tool and the PD Pal study, Per Odin, professor at Lund University and senior attending physician at Skåne University Hospital in Lund, hopes to be able to improve the care of Parkinson’s patients. Eve

https://www.multipark.lu.se/article/faster-and-better-treatment-parkinsons-disease-manage-pd-tool - 2026-05-09

Three out of Lund University’s four most cited scientists are research leaders at MultiPark, according to Clarivate’s report for this year. The highly anticipated annual list identifies researchers who demonstrated significant influence in their chosen field or fields through the publication of multiple highly cited papers during the last decade. Their names are drawn from the publications that ra

https://www.multipark.lu.se/article/majority-most-cited-researchers-lund-university-belong-multipark - 2026-05-09

During his Ph.D. studies, Alexander Svanbergsson has established a modelling system to screen for factors affecting the aggregation of alpha-synuclein in Parkinson’s disease. On the 3rd of December, it is time for him to defend his work supervised by Prof. Jia-Yi Li. Now, Alexander tells us about his research in the research group Neural Plasticity and Repair at MultiPark. What is your research ab

https://www.multipark.lu.se/article/phd-defence-interview-alexander-svanbergsson - 2026-05-09