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Early Predictors of Mortality in Patients with COPD, in Relation to Respiratory and Non-Respiratory Causes of Death - A National Register Study

Background: Both single factors and composite measures have been suggested to predict mortality in patients with chronic obstructive pulmonary disease (COPD) and there is a need to analyze the relative importance of each variable. Objective: To explore the predictors of mortality for patients with COPD in relation to respiratory, cardiac, and malignant causes, as well as all causes of death. Metho

Automatic diagnosis of melanoma using hyperspectral data and GoogLeNet

Background: Melanoma is a type of superficial tumor. As advanced melanoma has a poor prognosis, early detection and therapy are essential to reduce melanoma-related deaths. To that end, there is a need to develop a quantitative method for diagnosing melanoma. This paper reports the development of such a diagnostic system using hyperspectral data (HSD) and a convolutional neural network, which is a

Effect of selective IK,ACh inhibition by XAF-1407 in an equine model of tachypacing-induced persistent atrial fibrillation

Background and Purpose: Inhibition of the G-protein gated ACh-activated inward rectifier potassium current, IK,ACh may be an effective atrial selective treatment strategy for atrial fibrillation (AF). Therefore, the anti-arrhythmic and electrophysiological properties of a novel putatively potent and highly specific IK,ACh inhibitor, XAF-1407 (3-methyl-1-[5-phenyl-4-[4-(2-pyrrolidin-1-ylethoxymethy

A combined effect of anti-HPA-1a and anti-HLA Class I in pregnancy?

Background: Maternal anti–human leukocyte antigen (HLA) Class I is commonly detected alongside anti–human platelet antigen (HPA)-1a in fetal and neonatal alloimmune thrombocytopenia (FNAIT). Little is known regarding whether the presence of anti-HLA Class I may exert an additive effect on the risk and severity of FNAIT. Methods and Materials: We reanalyzed samples originally collected as part of a

Multimodal single-cell analysis reveals distinct radioresistant stem-like and progenitor cell populations in murine glioma

Radiation therapy is part of the standard of care for gliomas and kills a subset of tumor cells, while also altering the tumor microenvironment. Tumor cells with stem-like properties preferentially survive radiation and give rise to glioma recurrence. Various techniques for enriching and quantifying cells with stem-like properties have been used, including the fluorescence activated cell sorting (

The interaction between macroprudential and monetary policies: The cases of Norway and Sweden

To shed light on the interaction between macroprudential and monetary policies, we study the inward transmission of foreign monetary policy in conjunction with domestic macroprudential and monetary policies in Norway and Sweden. Using detailed bank-level data we show how Norwegian and Swedish banks’ lending reacts to monetary policy surprises arising abroad, controlling for the domestic macroprude

Maximizing Safety in the Conduct of Alzheimer's Disease Fluid Biomarker Research in the Era of COVID-19

The coronavirus disease 2019 (COVID-19) pandemic led to an abrupt halt of many Alzheimer's disease (AD) research studies at sites spanning the world. This is especially true for studies requiring in-person contact, such as studies collecting biofluids. Since COVID-19 is likely to remain a threat for an extended period, the resumption of fluid biomarker studies requires the development and implemen

Once Upon a Time in Quantum Computing: A Grounded Theory Study on Hardware Purchasing

Quantum computing is a potentially disruptive field, and a significant amount of resources are invested in technology advancements. The business-related research, however, is a relatively unexplored area. This master’s thesis explores the key factors that buyers consider when purchasing quantum computing hardware, the perception towards start-ups versus established quantum computing companies, and

Missbruk - en beroendesjukdom eller bristande vandel? En kvalitativ dokumentstudie om missbruk, i ljuset av förslaget att karaktärisera missbruk bland utländska medborgare som bristande vandel

Föreliggande studie tar avstamp i den massiva kritik som kommit mot Tidöavtalets förslag att använda missbruk som exempel på bristande vandel och skäl för utvisning av utländska medborgare. Flera representanter inom vård- och omsorg har uttryckt att detta inte överensstämmer med dagens kunskap om missbruk som en beroendesjukdom. Studien har en socialkonstruktivistisk utgångspunkt och använder en k

"Jag vill stänga in min broder, och låta kvinnan i min kropp få leva" Kön och sexualitet i den tidiga svenska transrörelsen, 1964-1969

This essay deals with the early trans movement in Sweden, which started in the sixties. Through the personal archive of Eva-Lisa Bengtson, activist and co-founder, it presents the groups Transvestia and FPE-NE (Full personality Expression, Northern Europe) as the first organisations to be started by and for any gender non-conforming people in Sweden. Their primary target group were heterosexual, m

Statistical analysis of LDMX data

This thesis explores a statistical framework for analysing LDMX data. It uses pre-built functions in the ROOT framework to calculate likelihoods and confidence levels (CL). Data, background and signal were generated in Monte Carlo simulations with a loose veto on signal in the Hcal with simple systematic uncertainties (for the background and signal) created by varying this selection. The data sets

EUs roll i förvaltning och dess effekter: Från direkt styre till flernivåstyre

The EU carries out several of its’ goals through programmes. From sustainable energy, improved social welfare and regional development. One way this is done is through the financing and managing of various programmes. Some of these programmes are managed through shared management in how they function. Meaning that the EU are co-funding programmes that are in turn managed by local governments in it

Prevalence of SDG-Washing: An Empirical Analysis on Large Listed European Companies

The sustainable development goals (SDGs) were introduced in 2015 to steer worldwide progress towards a sustainable, inclusive and prosperous path. Since then companies have gradually taken up the goals and are today actively reporting contributions to the goals. However, with this, also a novel concept of SDG-washing has emerged – companies claiming to contribute to the SDGs but in reality not doi

Pretty in Pink: En undersökning av romance-imprints på den svenska bokmarknaden

Syftet med uppsatsen är att belysa utvecklingen av romance-imprints på den samtida bokmarknaden i Sverige, och hur dessa arbetar med värdeförhandling av romancegenren. Detta görs genom att undersöka två imprints – Lovereads och HarperLove – och deras kurering av författarskap, deras marknadsföring och visuella profil, samt vad som kännetecknar deras relation med sina läsare. Uppsatsens frågeställn

Navigating Uncertainty: Exploring mechanisms roles in changing work conditions

Abstract Titel: Navigating Uncertainty: Exploring mechanisms roles in changing work conditions Seminar date: 1 June 2023 Authors: Lucas Ekedahl, Oscar Steinvik, Johan Ottosson Course: FEKH99, Examensarbete i Entreprenörskap och Innovation, 15 Högskolepoäng. Supervisor: Ziad El-Awad Key word: Mechanisms, Small Business, Remote Work Contingency Theory and Crises. Thesis question: How do small busine

Microfluidic flow splitter shape optimization for high throughput

Due to an increasing incidence rate, the need for new effective methods for diagnosing cancer are of high importance. Studies have shown that circulating tumor cells, CTCs, have great potential as a diagnostic biomarker. Acoustophoresis is a label free method, capable of separating CTCs from red blood cells in a blood sample. In theory, this would enable better CTC detection than the gold standard