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Late diagnosis of HIV persists in Sweden : Differing social determinants among migrant and non-migrant people with HIV

Objective: To examine temporal changes in late diagnosis of HIV (LD) among migrant and non-migrant people with HIV in Sweden 2003–2023 and to assess demographic and socioeconomic risk factors for LD in these two populations. Methods: People with HIV diagnosed with HIV-1 in Sweden 2003–2023 were included (n = 6278). LD was defined as a first CD4+ T-cell count <350 cells/μL or an AIDS-defining event

Titanium Carbide MXene Synthesis by Etching of Titanium Aluminum Carbide in Acetic Acid Solution

Ti-MXene (Ti3C2Tz) is the most common member of a larger family of 2D materials widely explored due to a variety of possible applications. MXenes are mostly synthesized using strong acids like HF and HCl or using procedures that require elevated temperatures. Here, we present a new method for Ti3C2Tz preparation with a weak acid solution, which is more beneficial for mass production with reduced e

The Effect of Pharmaceutical Excipients on Protein Chemical Degradation Through Deamidation and Isomerization

Introduction: Therapeutic proteins are crucial in the treatment of a wide range of diseases. However, the proteins are sensitive to chemical degradation reactions, particularly deamidation and isomerization, which can compromise efficacy and safety. Formulation excipients, such as sugars and non-ionic surfactants, are commonly used to enhance stability, yet their effects on chemical degradation re

Evaluation of cancer cell membrane-disruption property of poly(vinyl alcohol)–ursodeoxycholic acid using 3D cancer–stromal models with macrophages

We developed a collagen microfiber-based 3D cancer tissue model that included monocytes. Using a sedimentation culture method, normal human dermal fibroblasts, endothelial cells, cancer cells, and THP-1 cells—that is, the human monocytes cell line—were cocultured under a high collagen density. THP-1 cells were differentiated into macrophages and showed M2-like polarization in the 3D tumor microenv

Methods and devices for providing operational feedback during power transfer in a wireless power transfer system

Disclosed is a method (310) for providing operational feedback during power transfer in a wireless power transfer system. The wireless power transfer system comprises a power transmit device arranged to transfer power over an inductive wireless power transfer interface operating at a transmit frequency to a power receive device. The wireless power transfer system is adapted to transfer information

Eight recommendations for advancing blue Nature-based Solutions

Crises narratives surrounding the societal challenges of biodiversity loss, climate change, and human health and well-being dominate current debates in global environmental politics. These challenges are deeply interconnected and require transformative and integrated change. Marine and coastal Nature-based Solutions (blue NbS) are an opportunity to minimise harmful human impacts on these ecosystem

Activities and Time Spent on Rehabilitation in Scandinavian ICUs : A Cross-Sectional Survey Among Healthcare Professionals

Introduction: Survivors of critical illness commonly experience physical, cognitive, and psychological impairments. Early rehabilitation may mitigate these impairments; however, how rehabilitation practices are perceived and implemented by healthcare professionals in intensive care unit (ICU) remains insufficiently described. This study aimed to describe healthcare professionals' perceptions of re

Scaling of components in critical long-range geometric random graphs on the 2-dim torus

We consider random graphs on the set of N2 vertices placed on the discrete 2-dimensional torus. The edges between pairs of vertices are independent, and their probabilities decay with the distance ρ between these vertices as (Nρ)−1. This is a versatile example of an inhomogeneous random graph that is not of rank 1. Here, we study the critical phase: the main result is the weak limit of the size of

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Kapitlet diskuterer de balancegange mellem nærhed og distance, som pædagoger foretager i mødet med nytilkomne familier med flygtningebaggrund. Mange pædagoger vil gerne give ekstra hjælp til nytilkomne børn og deres familier, men i dette engagement udfordres på den ene side grænserne mellem professionelle og private relationer, på den anden side balancen mellem medfølelse og offergørelse. Kapitlet

Altered frontal and occipital cortical microstructure in obsessive-compulsive disorder - a multisite mega-analysis

Alterations in cortical morphology have consistently been reported in obsessive-compulsive disorder (OCD). However, the microstructural properties of the cortex in OCD, including intracortical myelination, remain far less explored. The contrast between signal intensity in gray and subjacent white matter from T1-weighted magnetic resonance imaging (MRI), i.e. the gray/white matter contrast (GWC), i

Adaptive attention-based model for 5G radio-based outdoor localization

Radio-based localization in dynamic environments, such as urban and vehicular settings, requires systems that efficiently adapt to varying signal conditions and environmental changes. Factors like multipath interference and obstructions introduce different levels of complexity that affect the accuracy of the localization. Although generalized models offer broad applicability, they often struggle t

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Forældre med flygtningebaggrund har, som alle andre forældre, store forhåbninger til deres børns fremtid. I modsætning til andre familier skal forældre med flygtningebaggrund imidlertid hjælpe deres børn til rette i et samfund, de selv er i gang med at lære at kende, og hvor varigheden af deres ophold ofte er præget af uvished. Denne bog bringer fokus på de dilemmaer og pædagogiske balancegange, d

Development and function of specified thymic iNKT1 cells critically depend on an Ets1-Tbet transcription factor axis

Invariant natural killer T 1 (iNKT1) cells are prototypic interferon γ-producing, innate-like T lymphocytes that play crucial roles in protection against pathogen infection and cancer. In the thymus, where these cells develop, iNKT cells contribute to the recruitment of antigen-presenting cells and promote T cell tolerance. Although the transcriptional programs guiding iNKT cell specification are

Exploring self-care practices, experiences, and interventions among adolescents and young adults with type 1 diabetes in Sub-Saharan Africa : a scoping review protocol

This scoping review aims to systematically explore the extent, nature, and gaps in the existing literature on self-care practices among adolescents and young adults aged 10–24 years living with type 1 diabetes mellitus (T1D) in Sub-Saharan Africa. The review will examine self-care knowledge, attitudes, practices, perceived barriers and facilitators, and interventions developed to support self-care