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Popular Abstract in Swedish Många av dagens stora folksjukdomar, såsom cancer, diabetes och hjärt-kärlsjukdomar, kopplas i allt högre grad samman med olika riskfaktorer som beror på förändringar i arvsmassan. Dessa nya kopplingar har möjliggjorts tack vare den extrema utveckling av genetiska mätmetoder som har skett under de senaste 15 åren. Med de nya metoderna kan förekomsten och aktiviteten hosThis thesis deals with methods for extracting robust and relevant information from high-dimensional data sets, and statistically guided visualization methods for representing the data in an informative and easily accessible way. High-dimensional data sets are becoming increasingly prevalent in many different scientific disciplines. In this thesis, we focus particularly on so called "omics" data. T

Venous thrombosis is a major medical problem annually affecting millions of individuals worldwide. It is a typical multifactorial disease, the pathogenesis involving both environmental and genetic risk factors. A single point mutation in the gene of coagulation factor V (FV), which results in the replacement of Arg506 with a Gln (FV Leiden) is the most common genetic risk factor known to date. The

Översättning av ett reportage från Roths resa i Sovjetunionen 1926.

Systemic or intracerebral delivery of neural stem and progenitor cells (NSPCs) and activation of endogenous NSPCs hold much promise as potential treatments for diseases in the human CNS. Recent studies have shed new light on the interaction between the NSPCs and cells belonging to the innate and adaptive arms of the immune system. According to these studies, the immune cells can be both beneficial

To evaluate relationships between lipid-lowering therapy, inflammation, and 3-year mortality in critical limb ischemia (CLI), 259 consecutive CLI patients underwent evaluation of medication, tumor necrosis factor-alpha, interleukin-6 (IL6), neopterin, high-sensitivity C-reactive protein (hs-CRP), 8-epi-PGF2alpha, and endothelin-1. Mortality was assessed after 3 years. Sixty-one patients (24%) were

A rate R=5/20 hypergraph-based woven convolu- tional code with overall constraint length 67 and constituent con- volutional codes is presented. It is based on a 3-partite, 3-uniform, 4-regular hypergraph and contains rate R=3/4 constituent convolutional codes with overall constraint length 5. Although the code construction is based on low-complexity codes, the free distance of this construction, c

Persons with a Middle Eastern background represent a minority in Sweden which has significantly increased in size over recent years. The purpose of the present study was to explore the elements that shape the experiences and perceptions of clients with a Middle Eastern background living by Muslim norms who received occupational therapy in mental health care at the time of participating in the stud

BACKGROUND.: To prepare a highly immunized recipient for heart transplantation, reduction of high levels of cytotoxic antibodies against human leukocyte antigen (HLA) was deemed essential to prevent antibody-mediated graft failure. METHODS.: Antibodies were analyzed by lymphocytotoxic and solid-phase assays. The pretransplant desensitization treatment protocol included daily tacrolimus and mycophe

There is a widespread perception that camera surveillance has a negligible effect on crime prevention. These notions are largely based on conclusions from research studies that are difficult to transfer to Swedish conditions. Better research is needed on how camera surveillance works in a Swedish context.

The post-failure convergence of shortest path routing (SPR) protocols used in IP networks can be too slow to meet the restrictive requirements (i.e. maximum allowable delay, jitter, etc.) of the multimedia services and therefore new protection/restoration mechanisms combined with IP routing are of interest. The article addresses the optimization of three potential rerouting mechanisms based on the

In this era of wireless hysteria, with continuous technological advances in wireless communication and new wireless technologies becoming standardized at a fast rate, we can expect an increased interest for wireless networks, such as ad hoc and mesh networks. These networks operate in a distributed manner, independent of any centralized device. In order to realize the practical benefits of ad hoc

Popular Abstract in Swedish Avhandlingen pressenterar resultat från fyra studerade områden; En undersökning av hur nya kolvrörelser (volym-vevvinkel relationer) påverkar utsläpp, effekt och verkningsgrad; En undersökning av hur kväveoxid påverkar självantändning och knack; En undersökning av hur vätgas och reformerad metanol (RMG) kan utnyttjas som bränsle, dels i vanliga tändstiftsantända (SI) moThe results presented in this thesis can be divided into four areas of investigation: Investigation of the effect of new volume-crank angle relations on engine emissions, power and efficiency; investigation of nitrogen oxides effect on auto ignition and knock in SI engines; investigation of premixed SI and HCCI engine operation with the alternative fuels hydrogen and reformed methanol gas (RMG); s

In this paper the Petersen and composition matrices that modellers are now familiar with are used as a basis to construct interfacing models between subsystems considered in wastewater treatment. Starting from continuity considerations and a set of transformation reactions between components used in the two models of the subsystems to be interfaced, a set of linear algebraic equations needs to be

This book is about how we verbally formulate thoughts about pictures, scenes, and visual events. The focus of the analysis lies on spoken descriptions from a communicative and cognitive perspective.