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Portable and autonomous analytical instrumentation is becoming more important. Portable instrumentation can be designed via the miniaturization approach and this is a challenging task due to: (i) the limited battery power supply, (ii) a low number of mechanical and moving parts allowed in the design and (iii) susceptibility to changing environment and temperature fluctuations. In this work we desc
BACKGROUND: Factor VIII (FVIII) and its carrier protein von Willebrand factor (VWF) are associated with risk of arterial and venous thrombosis and with hemorrhagic disorders. We aimed to identify and functionally test novel genetic associations regulating plasma FVIII and VWF. METHODS: We meta-analyzed genome-wide association results from 46 354 individuals of European, African, East Asian, and Hi
Patients with heart failure with left ventricular (LV) dyssynchrony often do not respond to cardiac resynchronization therapy (CRT), indicating that the pathophysiology is insufficiently understood. Intracardiac hemodynamic forces computed from four-dimensional (4-D) flow MRI have been proposed as a new measure of cardiac function. We therefore aimed to investigate how hemodynamic forces are alter
Social entrepreneurship research highlights the collaborative nature of social entrepreneurial efforts. Further, acknowledging the embeddedness of social ventures in the wider socio-economic and cultural context, the literature stresses the need to move our analysis from the micro-level of intra-organisational practices to the meso-level of inter-organisational dynamics. To answer to these calls,
Background: Even though identical blood group matching between recipient and donor is preferred, it is still not clear by how much this improves the outcome for patients who received a lung transplant (LTx), or whether there is any survival benefit. Earlier studies have yielded ambiguous results and few have investigated long-term survival. The aim of this study is, therefore, to explore the diffe
Although microfinance is often thought of as a tool to address poverty in developing countries, it is also being introduced in a number of countries in the developed world. The paper presents a qualitative study of the first year of the introduction of microfinance to address vulnerable groups in Sweden. Savings banks and nonprofit organisations collaborated in the introduction of microfinance as
For polarized light to inform behaviour, the typical range of degrees of polarization observable in the animal's natural environment must be above the threshold for detection and interpretation. Here, we present the first investigation of the degree of linear polarization threshold for orientation behaviour in a nocturnal species, with specific reference to the range of degrees of polarization mea
Introduction to the Special issue on “Community-Engaged Scholarship”
Scholars in the field of social entrepreneurship are challenging the researchers to produce empirical research on the social dimension of this phenomenon. Drawing on Foucault, this paper proposes the notion of ‘social entrepreneurial rationality’ to capture the social dimension of social entrepreneurship. The article builds on a comparative case study of three social ventures, each adopting a diff
The last 20 years have seen a flood of studies of resistance, ranging from collective to individual acts of resistance, from the study of material aspects to its more ideational ones. Yet students of resistance have neglected the psychological dimension of everyday individual acts of resistance to power. This article is a first step to remedy that oversight. Inspired by Butler’s reading of Foucaul
It has been long known that hyperglycaemia-induced β-cell dysfunction precipitates type 2 diabetes (T2D) in insulin-resistant obesity, although the underlying mechanisms are still poorly defined. The few frequently used antidiabetic drugs on the market have still not satisfactorily demonstrated any long-lasting improvements of β-cell function and prevention of the disease. Islets synthesise and se
The enhanced vegetation growth by climate warming plays a pivotal role in amplifying the seasonal cycle of atmospheric CO2 at northern lands (>50° N) since 1960s. However, the correlation between vegetation growth, temperature and seasonal amplitude of atmospheric CO2 concentration have become elusive with the slowed increasing trend of vegetation growth and weakened temperature control on CO2 upt
OBJECTIVE: Exposure to hyperoxemia and hypoxemia is common in out-of-hospital cardiac arrest (OHCA) patients following return of spontaneous circulation (ROSC), but its effects on neurological outcome are uncertain, and study results are inconsistent. METHODS: Exploratory post hoc substudy of the Target Temperature Management (TTM) trial, including 939 patients after OHCA with return of spontaneou
Alternative fuels for combustion engines are becoming increasingly popular as society is pushing to phase out fossil energy to reduce CO2 emissions. The compression ignition (CI) engine has a high overall efficiency which makes it a valuable option for the transport fleet, despite the well known NOx and soot pollutants it emits. These two pollutants are emitted due to a combination of high local cAlternative fuels for combustion engines are becoming increasingly popular as society is pushing to phase out fossil energy to reduce CO2 emissions. The compression ignition (CI) engine has a high overall efficiency which makes it a valuable option for the transport fleet, despite the well known NOx and soot pollutants it emits. These two pollutants are emitted due to a combination of high local c
Forests dominate carbon (C) exchanges between the terrestrial biosphere and the atmosphere on land. In the long term, the net carbon flux between forests and the atmosphere has been significantly impacted by changes in forest cover area and structure due to ecological disturbances and management activities. Current empirical approaches for estimating net ecosystem productivity (NEP) rarely conside
