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Accumulation of acetate is a limiting factor in recombinant production of (R)-3-hydroxybutyrate (3HB) by Escherichia coli in high-cell-density processes. To alleviate this limitation, this study investigated two approaches: (i) deletion of phosphotransacetylase (pta), pyruvate oxidase (poxB), and/or the isocitrate lyase regulator (iclR), known to decrease acetate formation, on bioreactor cultivati

Increased awareness of environmental sustainability with associated strict environmental regulations has incentivized the pursuit of novel materials to replace conventional petroleum-derived plastics. Polyhydroxyalkanoates (PHAs) are appealing intracellular biopolymers and have drawn significant attention as a viable alternative to petrochemical based plastics not only due to their comparable phys

Biotechnologically produced (R)-3-hydroxybutyrate is an interesting pre-cursor for antibiotics, vitamins, and other molecules benefitting from enantioselective production. An often-employed pathway for (R)-3-hydroxybutyrate production in recombinant E. coli consists of three-steps: (1) condensation of two acetyl-CoA molecules to acetoacetyl-CoA, (2) reduction of acetoacetyl-CoA to (R)-3-hydroxybu

Since the rise of radical geography in the early 1970s, political economy has been crucial in examining the spatial dynamics of capital in economic geography. Marxist and non-Marxist (particularly institutionalist) economic geographers use political economy to challenge non-political economy approaches that ignore the relationship between microeconomic processes and their spatial manifestations an

Outbreaks of highly pathogenic avian influenza (HPAI) pose an escalating threat to global poultry supply chains, with their management highlighting reconfigurations in economic geography through the increasing centrality of actors and processes beyond the farm-level. Taking HPAI outbreaks in Denmark as our empirical focus, we argue that outbreaks and their management reveal poultry growers’ lack o

Shifting the concept of municipal wastewater treatment to recover resources is one of the key factors contributing to a sustainable society. A novel concept based on research is proposed to recover four main bio-based products from municipal wastewater while reaching the necessary regulatory standards. The main resource recovery units of the proposed system include upflow anaerobic sludge blanket

IntroductionSport-related concussion (SRC) is a major health concern in contact sports. Linear head acceleration (LHA) and rotational head acceleration (RHA) are central biomechanical markers, and anticipatory neck muscle activation may mitigate these forces. Evidence on how anticipation influences head kinematics, and whether sex differences exist, remains limited. This study compared head accele

This article examines the subversive mobilities and vernacular legal navigation of Uzbek migrants in Finland and Sweden, highlighting their tactical responses to restrictive Nordic migration regimes. Drawing on ethnographic fieldwork (2022–2025), including interviews, focus groups and digital ethnography, we explore how migrants with precarious statuses navigate legal ambiguity, administrative opa

Background: Halomonas boliviensis is a halophilic microorganism that accumulates poly(3-hydroxybutyrate) (PHB) using different carbons sources when nitrogen is depleted from the culture medium. This work presents an improved production of PHB using an air-lift reactor (ALR) that was fed with a concentrated solution of a carbon source, and was supplemented with an adequate airflow rate. Results: Si

Background: Lignocellulosic waste is a desirable biomass for use in second generation biorefineries. Up to 40% of its sugar content consist of pentoses, which organisms either take up sequentially after glucose depletion, or not at all. A previously described Escherichia coli strain, PPA652ara, capable of simultaneous consumption of glucose, xylose and arabinose was in the present work utilized fo

Wastewater-based epidemiology (WBE) can be used to track the spread of SARS-CoV-2 in a population. This study presents the learning outcomes from over two-year long monitoring of SARS-CoV-2 in Stockholm, Sweden. The three main wastewater treatment plants in Stockholm, with a total of six inlets, were monitored from April 2020 until June 2022 (in total 600 samples). This spans five major SARS-CoV-2

This is a scoping review of low-intensity, home-based interventions promoting learning for 11–17-year-olds in foster care. Research shows that children in out-of-home care fall behind in school compared to their peers. Interventions to improve learning outcomes for these children typically i) target young children or children aging out of care, and ii) require many resources to implement. Lo

Background: Laparoscopic cholecystectomy (LC) is performed by surgeons from various specialties and remains central to minimally invasive surgical training. This study assessed whether surgeon subspecialty affects patient outcomes and explored aspects of LC education. Methods: This population-based study included 46,700 LCs performed between 2020 and 2023, using data from the Swedish Registry for

Global usage of pharmaceuticals has led to the proliferation of bacteria that are resistant to antimicrobial treatments, creating a substantial public health challenge. Here, we investigate the emergence of sulfonamide resistance genes in groundwater and surface water in Patna, a rapidly developing city in Bihar, India. We report the first quantification of three sulfonamide resistance genes (sulI

IntroductionSport-related concussion (SRC) is one of the most common and concerning injuries in team sports, with potential long-term effects on athlete health and performance. Linear head acceleration (LHA) and rotational head acceleration (RHA) are central biomechanical markers of brain loading during impact. Yet, the magnitude of these accelerations during SRC events remains poorly synthesized

This dissertation discusses various issues relating to Iron Age settlements in the area around the central place of Uppåkra. Most of the sites have been excavated by contract archaeology. The discussion begins with a presentation of the material from the houses in the settlements, detailing the different construction types and discussing the functions and chronological aspects of the houses. The d

Wastewater monitoring is highly efficient in SARS-CoV-2 surveillance for tracking virus spread through travel, surpassing traditional airport passenger testing. This study explored the links between SARS-CoV-2 contents and variants from aircraft to city, assessing the impact of detected variants from international travellers versus the local population. A total of 969 variants using next-generatio

Från de första kyrkorna på 900-talet och fram till idag har kyrkor uppförts och försvunnit igen. Kyrkor har ersatts av nya på samma plats eller på andra platser. Kyrkor har även lagts ner av olika anledningar. Kyrkorna har således både ökat och minskat i antal. Idag har många kyrkor blivit övertaliga och används därför mer sällan, i några fall tillåts de förfalla, får nya funktioner eller säljs. TFrom the first churches in the 9th century to the present day, churches have been built and then disappeared again. Churches have been replaced by new ones in the same or other locations. Or churches have been closed for various reasons. The churches have thus increased in number and decreased again. Today, many churches have become redundant and are therefore used less frequently, in some cases t