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In recent years, countries, regions, municipalities and the EU Commission have introduced a significant number of innovation policy initiatives under the banner of ‘missions’, ‘societal challenges’, sustainability, and ‘transformation’, or systemic change. In parallel, there has been a rapidly growing body of literature seeking to analyze or assess these real-world manifestations of attempts to pi
Pyrolytic carbon derived from thermosetting polymer precursors is a promising electrode material for bioelectrochemical applications due to its structural robustness, chemical stability, biocompatibility, and amenability to surface modification. Crucially, it allows the integration of diverse nano- and microstructures on the electrode surface. In this study, we introduce pyrolytic carbon nanograss
As populations age, many countries are raising retirement ages and encouraging longer working lives. In Sweden, where old-age employment rates are already high, questions remain about how these patterns vary across regions and labour market segments. This article provides a comprehensive overview of old-age employment trends from 1990 to 2021, using detailed population register data. While employm
Background: Sport-related concussion (SRC) is a common and complex injury in athletic populations. Linear head acceleration (LHA) and rotational head acceleration (RHA) are key biomechanical factors believed to contribute to SRC, each through distinct mechanisms. Evaluating head impact magnitudes across different sports, athlete populations, and measurement methods is essential for advancing SRC i
How do actors overlook uncomfortable information? We add to the understanding of how potential problems can be ignored over long periods, in spite of recurrent warnings. Ignoring then becomes a dynamic process of responding to evolving ignoring ‘threats’ or triggers by combining knowledge-seeking and knowledge avoidance in ways that must be continuously legitimated, both in one’s own eyes and in t
Serglycin (SRGN) has been found overexpressed and secreted in glioblastoma (GBM), associated with tumorigenic signaling and poor prognosis. In this study, we aimed to elucidate the involvement of SRGN in the unfolded protein response (UPR), an oncogenic signaling pathway implicated in protein recycling and cell fate. Herein, we developed stably transduced LN-18shSCR GBM cells, expressing high leve
Purpose: Violence against women is a major public health concern. Comparative research on outcomes across different service providers remains limited. Method: Women seeking support from social welfare units or women’s shelters were recruited from six organizations in Sweden. A pre–post design was applied, with structured interviews and questionnaires at baseline and 1-year follow-up. Fifty-one womViolence against women is a major public health concern. Comparative research on outcomes across different service providers remains limited. Method: Women seeking support from social welfare units or women's shelters were recruited from six organizations in Sweden. A pre–post design was applied, with structured interviews and questionnaires at baseline and 1-year follow-up. Fifty-one women partic
Neurofilament light chain (NfL) is a promising biomarker of axonal injury across acute and chronic neurodegeneration, which can improve drug discovery and disease monitoring models. Traditional in vivo animal models cannot fully mimic human pathophysiology of neurodegenerative diseases (NDDs), but in vitro models based on human cells solve this problem, reducing the time and cost of drug testing.
The article examines Starbucks as a global cultural symbol whose success varies sharply across contexts, contrasting its exceptional growth in South Korea with its near failure in Sweden. In Korea, Starbucks has thrived by pioneering localized marketing and spatial design strategies, enjoying unusual autonomy from headquarters and shaping new consumption patterns; however, recent controversies hav
INTRODUCTION: Early detection of Alzheimer's disease (AD) is critical for timely intervention as disease-modifying treatments emerge. Speech-based digital biomarkers offer scalable options for remotely capturing speech-derived functional changes associated with early cognitive decline, but validation across real-world populations remains limited.METHODS: We evaluated the speech biomarker for cogni
A detailed understanding of excited-state evolution is critical to realizing the full potential of abundant-metal coordination complex photosensitizers. Here, we show how wide-band optical transient absorption spectroscopy (oTA) can delineate the complete energy relaxation pathway of the photoexcited state of Fe(ii) polypyridyl complexes supported by benzannulated diarylamido ligands. By covering
