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Role of polysaccharides in food, digestion, and health

Polysaccharides derived from plant foods are major components of the human diet, with limited contributions of related components from fungal and algal sources. In particular, starch and other storage carbohydrates are the major sources of energy in all diets, while cell wall polysaccharides are the major components of dietary fiber. We review the role of these components in the human diet, includ

Compton scattering from the deuteron and extracted neutron polarizabilities

Differential cross sections for Compton scattering from the deuteron were measured at MAX-Lab for incident photon energies of 55 and 66 MeV at nominal laboratory angles of 45degrees, 125degrees, and 135degrees. Tagged photons were scattered from liquid deuterium and detected in three NaI spectrometers. By comparing the data with theoretical calculations in the framework of a one-boson-exchange pot

On Reconstruction of Cortical Functional Maps Using Subject-Specific Geometric and Connectome Eigenmodes

Understanding the interplay between human brain structure and function is crucial to discern neural dynamics. This study explores the relation between brain structure and macroscale functional activity using subject-specific structural connectome eigenmodes, complementing prior work that focused on group-level models and geometry. Leveraging data from the Human Connectome Project, we assess accura

Combinatorial DNMTs and EZH2 inhibition reprograms the H3K27me3 and DNAme-mediated onco-epigenome to suppress multiple myeloma proliferation

Comprehensive epigenomic studies in multiple myeloma (MM) that unravel the connections between major epigenetic regulators, their intertwined collaboration and the potential of combinatorial targeting remain limited. Utilizing ChIP-seq, ATAC-seq, RNA-seq, and DNA methylation (DNAme) data, we generated whole-genome chromatin annotations from normal plasma cells and MM patients, revealing epigenomic

KChIP3 fosters neuroinflammation and synaptic dysfunction in the 5XFAD mouse model of Alzheimer’s disease

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder marked by β-amyloid (βA) accumulation, neuroinflammation, excessive synaptic pruning, and cognitive decline. Despite extensive research, effective treatments remain elusive. Here, we identify potassium channel-interacting protein 3 (KChIP3) as a key driver of AD pathology using the 5XFAD mouse model. KChIP3 levels were significan

Induction of murine experimental autoimmune myocarditis – technical details, implementation and evaluation

Introduction: Myocarditis is a complex cardiac disorder with multifactorial etiology, characterized by myocardial inflammation, cardiomyocyte damage, and fibrosis. Left untreated, myocarditis may lead to acute and chronic heart failure and life-threatening arrhythmias. Reliable experimental models of myocarditis are required to study the underlying pathological mechanisms of the disease and to dev

Land use modelling needs to better account for multiple cropping to inform pathways for sustainable agriculture

Multiple cropping, the simultaneous cultivation of several crops in space or time, is a global practice essential for intensifying and diversifying agriculture. Despite its substantial impact on environmental and socioeconomic outcomes of farming, multiple cropping is hardly accounted for in assessments of global food production, sustainability, and climate impacts. Such studies, often relying on

How energy and chemistry converge for a fossil-free future

The chemical industry must undergo a dual transformation: electrifying energy use and defossilizing carbon feedstocks. This paper, developed by ENGIEs Scientific Council, examines how energy and chemistry can converge to enable this shift. We assess the roles of biomass, recycled plastics, and CO2 as sustainable carbon sources and explore the enabling potential of electrification, low-carbon hydro

Super-resolution stimulated X-ray Raman spectroscopy

Propagation of intense X-ray pulses through dense media has led to the observation of phenomena such as atomic X-ray lasing1,2, self-induced transparency3 and stimulated X-ray Raman scattering (SXRS)4. SXRS has been long predicted as a means to launch and probe valence-electron wavepackets and as a building block for nonlinear X-ray spectroscopies5,6. However, experimental observations of SXRS to

Structural insights into AQP3 channel closure upon pH and redox changes reveal an autoregulatory molecular mechanism

Regulation of intracellular levels of reactive oxygen species (ROS) remains poorly understood. Aquaporin 3 (AQP3) facilitates the membrane transport of hydrogen peroxide (H2O2), a key ROS signaling molecule. Here we elucidate the molecular mechanism of AQP3 and show that its regulatory properties are both pH dependent and autoregulated by H2O2. Using single particle cryo-electron microscopy, we pr

Alpha synuclein co-pathology is associated with accelerated amyloid-driven tau accumulation in Alzheimer’s disease

Background: Aggregated alpha-Synuclein (αSyn) is a hallmark pathology in Parkinson’s disease but also one of the most common co-pathologies in Alzheimer’s disease (AD). Preclinical studies suggest that αSyn can exacerbate tau aggregation, implying that αSyn co-pathology may specifically contribute to the Aβ-induced aggregation of tau that drives neurodegeneration and cognitive decline in AD. To in

Differences in sexual violence against younger and older adults in complex humanitarian settings : a retrospective analysis from Médecins Sans Frontières in 2019-24

BACKGROUND: Sexual violence against older adults in humanitarian settings is poorly documented, leading to gaps in prevention and delivery of support services. This study aimed to document differences in assault characteristics between younger and older adults, by sex and displacement and disability status and region. METHODS: This retrospective, descriptive observational, multi-country study incl

Kinetics of Biomarkers for Therapeutic Assessment in Swiss Mice Infected with a Virulent Trypanosoma cruzi Strain.

Chagas disease (CD), caused by Trypanosoma cruzi, is a neglected tropical illness affecting 6-8 million people in Latin America. Reaching scholarly consensus on the host response to T. cruzi infection remains a significant challenge, primarily due to substantial heterogeneity in outcomes driven by both the choice of animal model and the infecting parasite's discrete typing unit (DTU). This varia

The Role of RB1 and Secondary Genomic Changes in the Development of Spindle Cell and Pleomorphic Lipomas

Spindle cell lipomas (SCL) and pleomorphic lipomas (PL) are today considered a single tumor entity (SCLPL). Atypical SCLPL, in contrast, represents a recently recognized related but distinct entity. Here we explored the correlation between genomic features and morphological aspects of SCLPL and atypical SCLPL and the role of the RB1 gene in tumor development. Seventy-one samples from 68 patients w

The changing landscape of multimodality imaging in congenital heart disease : white paper

The congenital heart disease (CHD) population has seen substantial growth due to advancements in paediatric cardiac care, cardiothoracic surgery, anaesthesia, and intensive care. Although improved surgical interventions have enhanced survival rates for even the most severe defects, such as hypoplastic left heart syndrome, most CHD patients remain palliated rather than cured, requiring lifelong exp

MDC diet history

The modified diet history methodology of the Malmö Diet Cancer cohort2016-09-05Edited by Elisabet Wirfält and Emily Sonestedt Resource persons:Dietary data collection at baseline: Ulrika Ericson (ulrika [dot] ericson [at] med [dot] lu [dot] se)Peter Wallström (especially supplements) (peter [dot] wallstrom [at] med [dot] lu [dot] se (peter[dot]vallstrom[at]med[dot]lu[dot]se)) Consultation on dieta

https://www.malmo-kohorter.lu.se/malmo-kost-cancer-mkc/mkc-kostmetod/mdc-diet-history - 2026-05-23

Microsoft Word - itteraturlista för Historisk metod.docx

Microsoft Word - itteraturlista för Historisk metod.docx HHI002F Litteraturlista för doktorandkursen Historisk metod Antagen av handledarkollegiet i historia 240906 Litteraturlistan är för åskådlighetens skull tematiskt uppbyggd. Kursen fokuserar på ett antal teman, och litteraturen listas under respektive temarubrik. Litteraturen omfattar ca 1159 sidor. Könsfördelningen bland författarna till ver

https://www.hist.lu.se/fileadmin/user_upload/forskarskolan_hist/itteraturlista_foer_Historisk_metod.pdf - 2026-05-23

Japansk metod bra vid operation av tarmtumörer – Vetenskap och Hälsa

Japansk metod bra vid operation av tarmtumörer – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Japansk metod bra vid operation av tarmtumörer 2016-05-26 ⚠️ Den här artikeln är mer än 5 år gammal. Nya forskningsrön kan ha tillkommit. Vid Skånes universitetssjukhus har ett nytt sätt att ta b

https://www.vetenskaphalsa.se/japansk-metod-bra-vid-operation-av-tarmtumorer/ - 2026-05-22

EKG – Vetenskap och Hälsa

EKG – Vetenskap och Hälsa Vetenskap och hälsa Populärvetenskapligt om medicinsk forskning i Skåne Teman Podd Tidskrift Prenumerera Om webbplatsen Kontakt Sök Sök Etikett: EKG AI är bättre än människan på att bedöma långtids-EKG 2025-02-25 Vid besvär av bland annat oregelbunden hjärtrytm, yrsel eller svimning kan EKG behöva registreras under flera dygn – långtids-EKG – som sedan granskas för att hi

https://www.vetenskaphalsa.se/tag/ekg/ - 2026-05-22