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BACKGROUND: Patients with a high ventricular rate during atrial fibrillation (AF) are at increased risk of receiving inappropriate implantable cardioverter defibrillator shocks. The objective was to demonstrate the feasibility of high frequency atrioventricular-nodal stimulation (AVNS) to reduce the ventricular rate during AF to prevent inappropriate implantable cardioverter defibrillator shocks.M

Parkinsons sjukdom förknippas ofta med rörelsesymtom, som skakningar, stelhet och långsammare rörelser. Sjukdomen kan dock också påverka talet. Rösten kan bli svagare, mindre varierad eller mindre stabil, och uttalet kan bli svårare att kontrollera. Eftersom tal är enkelt att spela in och inte kräver några invasiva undersökningar är det intressant att undersöka om tal kan användas som en källa tilSpeech has become an increasingly important source of non-invasive information for Parkinson's disease detection, but much existing work still relies on sustained vowels. This thesis investigates whether carefully represented continuous speech can provide added predictive value over a strong sustained-vowel benchmark. Using the NeuroVoz corpus, sustained-vowel recordings were first used to est

Background: Swedish healthcare is in a period of transition with an expanding private sector. This study compares quality of outcome after groin hernia repair performed in a public or private healthcare setting. Methods: A cohort study based on data from the Swedish National Hernia Register combined with Patient-Reported Outcome Measures (PROMs) 1 year after groin hernia repair. Between September

Radio signals are used broadly as navigation aids, and current and future terrestrial wireless communication systems have properties that make their dual-use for this purpose attractive. Sub-6 GHz carrier frequencies enable widespread coverage for data communication and navigation, but typically offer smaller bandwidths and limited resolution for precise estimation of geometries, particularly in e

Background and objective: The treatment landscape of metastatic prostate cancer (mPCa) has evolved significantly over the past two decades. Despite this, the optimal therapy for patients with mPCa has not been determined. This systematic review identifies available predictive models that assess mPCa patients’ response to treatment. Methods: We critically reviewed MEDLINE and CENTRAL in December 20

INTRODUCTION: Amyloid beta and tau pathology are the hallmarks of sporadic Alzheimer's disease (AD) and autosomal dominant AD (ADAD). However, Lewy body pathology (LBP) is found in ≈ 50% of AD and ADAD brains. METHODS: Using an α-synuclein seed amplification assay (SAA) in cerebrospinal fluid (CSF) from asymptomatic (n = 26) and symptomatic (n = 27) ADAD mutation carriers, including 12 with known

The European Spallation Source, ESS, is a neutron research facility under construction in Lund, Southern Sweden. The Facility will produce neutrons by spallation, using a powerful linear accelerator to deliver protons to a tungsten target. In addition to the desired neutron production, a long list of radionuclides will be created as by-products of the nuclear reaction inside the target. The Swedis

The ability to generate and control movement is essential for human interactions and overall well-being. Neuromuscular impairment caused by neurological injuries and diseases, such as stroke or limb amputation, severely limits the ability of affected individuals to interact with the surrounding environment, necessitating advanced strategies for rehabilitation and restoration of motor function. Vol

Capturing ultrafast phenomena requires imaging techniques capable of resolving events occurring on femtosecond time scales. Traditional high-speed cameras are limited by electronic readout speeds and cannot reach the terahertz (THz) frame rates necessary to observe processes such as laser filamentation, plasma formation, or light-matter interactions in general. To overcome these limitations, this

OBJECTIVE: It has been proposed that remission should be maintained throughout the course of rheumatoid arthritis (RA); however, the evidence supporting this is limited. Physical function measured by the Health Assessment Questionnaire (HAQ) is a major outcome in RA, and HAQ is shown to be one of the strongest predictors of longterm outcomes. The purpose of this study was to investigate the physic

Deep flexor tendons of 30 rabbits were divided at the ankle level. The effects of unloading on the synthesis and content of matrix components, the synthesis of DNA, and dry weight were investigated. The reaction of the fibrocartilaginous and non-fibrocartilaginous segments were separately analyzed. The ability of the tendons to synthesize collagen during short-term culture and the contents of matr

Popular Abstract in Swedish Nästa år är det 400 år sedan Galileo Galilei för första gången riktade ett teleskop mot objekt på himlen. Allt sedan dess har teleskopet varit det viktigaste instrumentet för astronomins utveckling och med dess hjälp har vår kunskap om universum revolutionerats. Tack vare utvecklingen av teleskopet under dessa århundraden har allt ljussvagare objekt kunnat studeras, ochThis thesis presents the work on the design of, construction of, and finally observations with, an experimental setup comprising a small telescope equipped with adaptive optics. The facility has been assembled at Lund Observatory, where also observations on the sky have been made. The aim of this project was to gain hands-on knowledge in the development of a real adaptive optics system and eventua

This paper describes the development of a modular system of interactive tiles to support therapists’ in performing therapeutic activities together with impaired children in a swimming pool. Active Surfaces support mobile interactions and dynamic configuration of assemblies of tiles. Each tile represents an interactive unit, able to communicate with other tiles and to exchange data. The tiles can

Introduction: Persistent pharmaceutical contaminants, such as Platinum cytostatics, commonly used in cancer therapy, have been detected in water bodies at low concentrations. Electrochemical, photochemical and biological treatments for the removal and degradation of these contaminants are expensive and sometimes ineffective. Sorption methods are a viable and more efficient alternative. Objectives:

BACKGROUND: Acute kidney injury (AKI) is a serious complication after major surgical procedures. We examined the incidence, risk factors, and mortality of patients who sustained AKI after abdominal surgery in a large population-based cohort.METHODS: All patients who underwent open and laparoscopic abdominal surgery (excluding genitourinary and abdominal vascular procedures), between 2007 and 2014

Observations of polarization position angle (θ) standards made from 2014 to 2023 with the High Precision Polarimetric Instrument (HIPPI) and other HIPPI-class polarimeters in both hemispheres are used to investigate their variability. Multiband data were first used to thoroughly recalibrate the instrument performance by bench-marking against carefully selected literature data. A novel co-ordinate

Antibiotic resistance is a growing global concern, with many ecological niches showing a high abundance of antibiotic resistance genes (ARGs), including the human gut. With increasing indications of ARGs in infants, this study aims to investigate the gut resistome profile during early life at a wider geographic level. To achieve this objective, we utilized stool samples data from 26 studies involv

The 4MOST consortium is currently halfway through a Conceptual Design study for ESO with the aim to develop a wide-field (>3 square degree, goal >5 square degree), high-multiplex (>1500 fibres, goal 3000 fibres) spectroscopic survey facility for an ESO 4m-class telescope (VISTA). 4MOST will run permanently on the telescope to perform a 5 year public survey yielding more than 20 million spectra at