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Deoxyribonucleic acid or DNA is one of the most fundamental molecules of life as it encodes the basic structure of every living entity, including us. Not only is DNA responsible for precisely describing every single aspect that makes us, it also directly affects the world around us. Indeed, unlocking the genetic code embedded in DNA already enabled us to create new diagnostics that allow us to det
Citizens are not born, they are made. Based on fieldwork in two upper-secondary school classes in Sweden – an Introductory Programme class and a Social Science Programme class – this dissertation focuses on how pupils form their identities as citizens in a democratic society. Citizens are made in interaction with the society they inhabit, an interaction where power is always present. Although Swed
Through a unique combination of time-resolved single-molecule (cryo-TEM) and bulk measurements (light scattering and small-angle X-ray scattering), we provide a detailed study of the dynamics of stochastic DNA ejection events from phage λ. We reveal that both binding with the specific phage receptor, LamB, and thermo-mechanical destabilization of the portal vertex on the capsid are required for in
SynopsisVarious protolytic species of thiols RSH (thioglycolic acid, l-cysteine, dl-penicillamine, and glutathione) in rapid equilibria with each other reduce trans-[Pt(CN)4Cl2]2- in parallel, halide-bridged electron transfer reactions. A linear Brønsted correlation between the reactivity of the thiolate anions RS- and their basicity is observed. The mechanism derived might be used as a model for
A high quality benchmark for small variants encompassing 88 to 90% of the reference genome has been developed for seven Genome in a Bottle (GIAB) reference samples. However a reliable benchmark for large indels and structural variants (SVs) is yet to be defined. In this study, we manually curated 1235 SVs which can ultimately be used to evaluate SV callers ortrain machine learning models. We devel
This study aims to understand how goals of activation and gender equality interact in labor market programs directed towards activating unemployed participants. The study draws on interviews with 28 social workers and managers at four Swedish municipally governed labor market programs typically targeted towards poor, unemployed individuals with little to no attachment to the labor market or social
Aims: To investigate if any differences in unmet healthcare needs between persons registered at public and private primary care providers exist in Skåne (southernmost Sweden). Methods:The 2012 public health survey in Skåne was conducted with a postal questionnaire and included 28,029 respondents aged between 18 and 80 years. The study was cross-sectional. If the responder in the last three months
Coevolution occurs when species interact to influence one another's fitness, resulting in reciprocal evolutionary change. In many coevolving lineages, trait expression in one species is modified by the genotypes and phenotypes of the other, forming feedback loops reminiscent of models of intraspecific social evolution. Here, we adapt the theory of within-species social evolution, characterized by
A standard proposition in the migration literature is that emigrants are not drawn randomly from their source population, but rather compose a self-selected group in terms of labour market characteristics. Such self-selection refers to observed characteristics, such as education, or occupation, as well as unobserved characteristics such as cognitive abilities. However, due to data limitations, mos
Motivated by the pioneering activation-energy asymptotic analysis of strained laminar premixed flames in counterflow by Libby and his coworkers, a rate-ratio asymptotic analysis is carried out to elucidate the structure and predict the critical conditions of extinction of strained premixed methane flames. Steady, axisymmetric, laminar flow of two counterflowing streams: a reactive mixture stream a
Non-bee pollinators (NBP) are a group of species with very diverse ecology. Indeed, they inhabitvarious habitats, using these as nesting sites, for shelter, as source of food and as huntingground for prey. Depending on the life stage of species, NBPs can inhabit different areas andtheir overall contribution to pollination can be diverse. For example, adult butterflies mainlyforage on nectar, where
Background: The knowledge about air pollution effects on birth weight, prematurity and small for gestational age [SGA] in low-exposure areas is insufficient. Objectives: The aim of this birth cohort study was to investigate if low-level exposure to air pollution was associated with prematurity and foetal growth and if there are gender specific effects. Method: We combined high quality registry inf
The effects on driving performance of using a hands-free, mobile telephone were investigated in a pursuit-tracking task that simulated driving. Twenty subjects in two age groups, 19-26 years (median = 21 years) and 40-51 years (median 45·5 years), participated, with five males and five females in each group. The primary task was driving safely. The subjects drove for 20 min in each of three second
ABSTRACT: BACKGROUND: It is well known that physicians' night-call duty may cause impaired performance and adverse effects on subjective health, but there is limited knowledge about effects on sleep duration and recovery time. In recent years occupational stress and impaired well-being among anaesthesiologists have been frequently reported for in the scientific literature. Given their main focus o
Introduction/Aim of the Study. One way of investigating health trends at the population level is to study the physical performance and functional ability in different birth cohorts. The information obtained can be used to predict illness, disability, and future needs for care. However, contradictory findings have been reported when comparing the physical performance of older adult birth cohorts. T
Background: The management of cancer-related pain relies on access to opioids. When regular opioids are not tolerated, or are insufficient, methadone is an affordable and effective analgesic. Aim: The aim of the project was to describe the pattern of use and clinical experience of methadone in pediatric cancer pain at a governmental cancer hospital in Hyderabad, one of the four Indian cancer cente
This article examines the subjective understanding of success among members of three groups of children of immigrants from Mexico, North Africa and Turkey, in Dallas, Paris and Berlin respectively, by accounting for their educational and early labor market experiences. We utilize neo-assimilation and segmented assimilation theories and highlight their divergence with regards to downward assimilati
Program 3rd PhD conference on Sustainable Development, 29 September 2023 09:15- 09:45 Welcome and inspirational presentation – acceleration of progress The year of 2023 marks the mid-point of the implementation of the 2030 Agenda, which is based on 17 Sustainable Development Goals that includes ending poverty, reducing inequality and tackling climate change. Early efforts after the SDGs were adopt
