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The gut bacterial community affects immunity but not metabolism in a specialist herbivorous butterfly

Plant tissues often lack essential nutritive elements and may contain a range of secondary toxic compounds. As nutritional imbalance in food intake may affect the performances of herbivores, the latter have evolved a variety of physiological mechanisms to cope with the challenges of digesting their plant-based diet. Some of these strategies involve living in association with symbiotic microbes tha

The Malmö Offspring Study (MOS) : design, methods and first results

As cardio metabolic disease manifestations tend to cluster in families there is a need to better understand the underlying mechanisms in order to further develop preventive strategies. In fact, genetic markers used in genetic risk scores, important as they are, will not be able alone to explain these family clusters. Therefore, the search goes on for the so called missing heritability to better ex

Genetic and environmental determinants of peak bone mass in young men and women

Peak bone mass is an important risk factor for the development of osteoporosis in later life. Previous work has suggested that genetic, intrauterine, and environmental factors all contribute to the regulation of bone mass, but the ways in which they interact with each other to do so remain poorly understood. In this study, we investigated the relationship between peak bone mass and polymorphisms o

Loess provenance in the westernmost part of the lower Danube Basin, Serbia : Geochemical insights from the Velika Vrbica fluvial–eolian section

Our study examined the chemical composition of fluvial and eolian sediments at the Velika Vrbica multisection, located on the bank of the Danube River in eastern Serbia, within the westernmost part of the lower Danube (Dacian) Basin. The multisection comprises two discrete sections: an older 2.7 m thick fluvial section, and a younger 11.2 m thick loess-paleosol sequence (LPS). These are exposed al

Multi-Value Plaintext-Checking and Full-Decryption Oracle-Based Attacks on HQC from Offline Templates

The Hamming Quasi-Cyclic (HQC) key encapsulation mechanism (KEM), recently selected by NIST for standardization in the Post-Quantum Cryptography (PQC) process, distinguishes itself through its efficiency, robust design based on hard decoding problems in coding theory, and well-characterized decryption failure rates. Despite its selection, practical security concerns arise from implementation threa

On affordance-based, autoethnographic music research

Recent years has seen increasing interest in the concept of affordances in music performance research. Hereby, the agency of musical instruments is understood as defined by the perceived opportunities for action emerging through the sensorimotor relationship (i.e. the continuous interaction between musician and instrument). As such, it is an analytical perspective that highlights material and embo

Epigenetic regulatory role of MORC2 in human brain development

Close encounters of the TE kind: molecular consequences of MORC2 mutations Nearly half of our DNA is composed of transposable elements (TEs), sequences that can copy and move around within the genome. When they move, they can disrupt the stability of our genome and cause damage to our cells. In response to that, cells have evolved mechanisms to minimize their movements. One protein that repress

Insights from Single-cell Omics - Cellular Heterogeneity as a Foundation of Clinical Outcome in Chronic Myeloid Leukemia

The BCR::ABL1 tyrosine kinase inhibitors (TKIs) in CML represent a paradigm for molecularly targeted therapy. However, clinical outcomes - rate/depth of response, treatment-free remission (TFR), progression to blast crisis (BC) - and adverse events vary among patients. While additional somatic mutations have been invoked to explain varying clinical outcomes, we here propose a complementary perspec

Anpassning för personer med funktionsnedsättning i arbetslivet - Arbetsgivarens ansvar för att motverka bristande tillgänglighet

År 2015 infördes bristande tillgänglighet som en självständig diskrimineringsform i den svenska diskrimineringslagen, i syfte att stärka delaktigheten i arbetslivet för personer med funktionsnedsättning. Trots reformen visar statistik att skillnader i sysselsättning, arbetsförmåga och upplevd diskriminering fortsatt är betydande i jämförelse med övriga befolkningen. Detta aktualiserar centrala rätIn 2015, lack of accessibility was introduced as a separate form of discrimination in the Swedish Discrimination Act. The reform aimed to improve access to employment for people with disabilities. Despite this change, statistics show that large differences in employment, work capacity and experiences of discrimination remain compared to the rest of the population. This raises important legal quest

Effektivt rättsmedel eller otillräcklig gottgörelse? En analys av konventionsskadeståndets förenlighet med Europakonventionens krav på effektiva rättsmedel

Den svenska statens primära ansvar att garantera skyddet av de grundläggande fri- och rättigheterna som följer av den europeiska konventionen om skydd för de mänskliga rättigheterna och de grundläggande friheterna (Europakonventionen) vilar bland annat på Sveriges förpliktelser som part till Europakonventionen. Detta ansvar har inneburit en betydande påverkan på den svenska skadeståndsrätten. Mer The Swedish state’s primary responsibility to guarantee the protection of the rights and freedoms set forth in the Convention for the Protection of Human Rights and Fundamental Freedoms (the Convention) is, among other things, based on Sweden’s obligations as a party to the Convention. This responsibility has significantly impacted Swedish tort law. More specifically, it concerns the ability of in

Infrared thermography is a useful tool in research on thermoregulation and evolution of heat tolerance

Non-invasive methods for measuring thermal tolerance and thermoregulation in large numbers of individuals under natural environmental conditions are useful to understand the capacity of species to adapt to future climate scenarios. Infrared thermography (IRT) is one such tool in research on thermal adaptation, but concerns have been raised about its reliability, specifically the correlation betwee

Effect of a standardized meal on inflammatory biomarkers

The digestion of food is known to have significant hemodynamic and metabolic effects where many have not been fully investigated. The potential effect of food intake could be interesting both from a physiological point of view and from a methodological point of view, as it could affect when blood samples are collected. The objective of this study was to investigate the effect of food intake on 143

Wireless Indoor Positioning Using Channel Charting: A Comparison of Deep and Graph Neural Networks

Indoor positioning is a challenging problem due to complex environments, signal attenuation, and multi-path effects. A promising approach to this problem is channel charting on wireless networks, where high-dimensional channel state information (CSI) is mapped into a low-dimensional latent space, which preserves spatial relationships in a self-supervised manner. Channel charting can be deep learni

Professional judgements in collaboration

Although intimate partner violence is far from a new problem in society, it has lately gained increased attention both by governments and by the research community. In 2007, the Swedish government issued an action plan for “combating men’s violence against women, violence and oppression in the name of honour and violence in same-sex relationships” (2007/08:39), which included a call for increased

Kustlinjeutveckling vid Ystad Sandskogs västra strand: Modellering i ShorelineS med fokus på kustparallell sedimenttransport och kusterosion

I följande examensarbete undersöks den morfologiska kustlinjeutvecklingen vid den västra stranden i Ystad Sandskog med fokus på kusterosion och längsgående sedimenttransport. Kuststräckan är historiskt och fortsatt erosionsutsatt och ligger i nära anslutning till bebyggelser, infrastruktur och naturreservatet Sandskogen. För att motverka kustens tillbakadragning har flera kustskyddsåtgärder implemThis master thesis investigates the morphological shoreline development at the western beach of Ystad Sandskog, with a focus on coastal erosion and longshore sediment transport. The coastline is affected by erosion and is located close to residential areas, infrastructure and the nature preserve Sandskogen. Several coastal protection measures have been implemented to prevent ongoing shoreline retr

Kustlinjeutveckling vid Ystad Sandskogs västra strand: Modellering i ShorelineS med fokus på kustparallell sedimenttransport och kusterosion

I följande examensarbete undersöks den morfologiska kustlinjeutvecklingen vid den västra stranden i Ystad Sandskog med fokus på kusterosion och längsgående sedimenttransport. Kuststräckan är historiskt och fortsatt erosionsutsatt och ligger i nära anslutning till bebyggelser, infrastruktur och naturreservatet Sandskogen. För att motverka kustens tillbakadragning har flera kustskyddsåtgärder implemThis master thesis investigates the morphological shoreline development at the western beach of Ystad Sandskog, with a focus on coastal erosion and longshore sediment transport. The coastline is affected by erosion and is located close to residential areas, infrastructure and the nature preserve Sandskogen. Several coastal protection measures have been implemented to prevent ongoing shoreline retr