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Background: The panel of fluid- and imaging-based biomarkers available for neurodegenerative disease research is growing and has the potential to close important gaps in research and the clinic. With this growth and increasing use, appropriate implementation and interpretation are paramount. Various biomarkers feature nuanced differences in strengths, limitations, and biases that must be considere
Reproductive isolation among four sympatric small ermine moths (Yponomeuta) is analyzed in terms of niches in the sexual communication channel. Potential pheromone components were identified from pheromone gland secretions of Y. evonymellus, Y. cagnagellus, Y. padelius, and Y. vigintipunctatus by gas chromatography with flame ionization and electroantennographic detection and tested for behavioral
Today, the Internet of Things (IoT) is mainly associated with vertically integrated systems that often are closed and fragmented in their applicability. To build a better IoT ecosystem, the open IoT platform has become a popular term in the recent years. However, this term is usually used in an intuitive way without clarifying the openness aspects of the platforms. The goal of this paper is to cha
This article examines how the common law tort of negligence as developed in the United Kingdom can provide a helpful guidance for deconstructing and elucidating some of the disparate analytical issues that are subsumed under the umbrella of positive obligations under the European Convention on Human Rights (ECHR). Both frameworks, common law and ECHR, aim to delimit the circumstances where respons
The present study (n = 121) was investigating the mediating effects of frustrated basic psychological needs on the relationship between passive destructive leading behaviors, burnout symptoms and the willingness to leave. The concept of the three basic psychological needs (need for autonomy, competence, and relatedness) is embedded in the Self-Determination Theory. As independent variables the con
I denna studie har 88 körningar i en körsimulator analyserats i syfte att undersöka hur utformningen av en cirkulationsplats påverkar förarens val av ingångshastighet. Aspekterna radiestorlek, antal körfält och mötande trafik var av intresse och justerades i testerna. Syftet var att sedan ställa datan för varje parameter mot varandra och därmed kunna ta fram ett resultat. Simuleringsmiljön byggdIn this examination 88 test-drives in a driving simulator have been analyzed with the purpose to research if the design of a roundabout will affect a driver’s entry speed. The aspects size of the radius, number of lanes and oncoming traffic was of interest and were adjusted within the tests. The purpose was to collect data from every parameter and then compare them to each other to get a result.
Theories of predictive processing postulate that the brain continuously generates predictions about future linguistic input. Many different linguistic elements have been found to function as predictive cues. One such element is classifiers, i.e., morphemes that classify noun referents according to some semantic property. However, very few studies have so far investigated the predictive function of
Enzymes are dynamic entities, and their conformational dynamics are intimately linked to their function and evolvability. In this context, protein tyrosine phosphatases (PTPs) are an excellent model system to probe the role of conformational dynamics in enzyme function and evolution. They are a genetically diverse family of enzymes, with a highly conserved catalytic domain, identical catalytic mec
När en kris inträffar är det väsentligt att snabba och lämpliga beslut fattas för att begränsa dess konsekvenser. Studien har undersökt om GIS (geografiska informationssystem) kan stötta krishanteringen på lokal nivå. Ett exempel på hur GIS kan användas som många personer kommer i kontakt med i sin vardag är vägbeskrivningar genom tjänster såsom Google Maps, men det har en potential att göra så mBoth studies on and the application of GIS-systems during several disastrous events has shown a potential of the technology to facilitate for decision makers to make quick and suitable decisions to limit the impact of an event. In Sweden the primary responsibility for a crisis is held by the municipality in which the crisis occurs, which motivates an interest in investigating how GIS can support m
The outcomes of FDI have been examined in several studies throughout recent years. Most examinations acknowledge that FDI is a usual positive for the host country. FDI can create direct effects such as wealth flow to the acquiring country, job production, and technology transfer as well as a show impacts in the form of improved productivity, innovation and education. Adverse effects emerge when th
Havet och vattnet symboliserar för mig avkoppling och rekreation, likväl som träning och sport. Att blicka ut över havet eller en vattenspegel får mig att känna ett lugn och välbefinnande. Det här examensarbetet tog sin början då jag ville undersöka ett aktuellt ämne. Jag fick till min kännedom att det flytande badhuset Liljeholmsbadet invid Bergsunds strand på Södermalm i Stockholm hade stängts For me the ocean and water symbolize relaxation and recreation, as well as training and sport. To look out over the ocean or a water mirror makes me feel calm and relaxed. This thesis began with the idea to explore a current topic. I discovered that the floating bath Liljeholmsbadet at Bergsunds strand, Södermalm in Stockholm was in a bad condition and due to that the municipality of Stockholm de
After the wider deglaciation of Northern Europe, pioneer reindeer populations started to move into southern Scandinavia; however, this process is poorly understood. In this paper we aim to reconstruct dispersal processes of reindeer into southern and western Sweden from the Late Palaeolithic through to the Early Mesolithic, when reindeer disappear from the record. Has presence of reindeer in south
Over four decades, Indigenous Sámi individuals and communities have submitted to United Nations human rights treaty bodies, including the Human Rights Committee, several complaints in respect of the three Nordic countries Finland, Norway, and Sweden. Many of these Sámi rights cases have made important contributions to the understanding and application of Indigenous peoples’ rights globally, in add
PURPOSE OF REVIEW: This review aims to give an overview of recent advances in the clinical management of children <18 years of age with end-stage pulmonary hypertension refractory to conventional medical therapy.RECENT FINDINGS/SUMMARY: The increased awareness and characterization of pediatric pulmonary vascular disease has amounted more data toward creating an accurate, and comprehensive, risk pr
