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Physical activity and risk of Amyotrophic Lateral Sclerosis in a prospective cohort study.
Succinate independently stimulates full platelet activation via cAMP and PI3β kinase signaling.
A Novel Mechanism of Bacterial Toxin Transfer within Host Blood Cell-Derived Microvesicles.
Shiga toxin (Stx) is the main virulence factor of enterohemorrhagic Escherichia coli, which are non-invasive strains that can lead to hemolytic uremic syndrome (HUS), associated with renal failure and death. Although bacteremia does not occur, bacterial virulence factors gain access to the circulation and are thereafter presumed to cause target organ damage. Stx was previously shown to circulate b
Mitochondrial proteome analysis reveals altered expression of voltage dependent anion channels in pancreatic beta-cells exposed to high glucose
Magnet design for a low-emittance storage ring.
The MAX IV 3 GeV storage ring, currently under construction, pursues the goal of low electron beam emittance by using a multi-bend achromat magnet lattice, which is realised by having several consecutive magnet elements precision-machined out of a common solid iron block, 2.3-3.4 m long. With this magnet design solution, instead of having 1320 individual magnets, the MAX IV 3 GeV storage ring is b
Haemodynamic monitoring using arterial waveform analysis.
PURPOSE OF REVIEW: To describe the theory behind arterial waveform analysis, the different variables that may be obtained using this method, reliability of measurements and their clinical relevance. Areas for future research are identified. RECENT FINDINGS: The precision of cardiac output (CO) measurements varies considerably and deteriorates during haemodynamic instability. Significant device-to-
The use of magnetite nanoparticles for implant-assisted magnetic drug targeting in thrombolytic therapy.
Ribosomal DNA Organization Patterns within the Dinoflagellate Genus Alexandrium as Revealed by FISH: Life Cycle and Evolutionary Implications.
Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.
Synergies from Combined Pulp&Paper and Fuel Production
Abstract in Undetermined In this paper, the prospect of integrating a combined paper&pulp mill with fuel production via biomass gasification was investigated. In the study, three different types of gasifiers (circulating fluidised bed, entrained flow and indirect gasification) and three fuel processes (dimethyl ether, methanol and Fischer-Tropsch wax synthesis) were investigated using computer
Chondroadherin Fragmentation Mediated by the Protease HTRA1 Distinguishes Human Intervertebral Disc Degeneration from Normal Aging
Pharmacological stimulation of metabotropic glutamate receptor type 4 in a rat model of Parkinson's disease and l-DOPA-induced dyskinesia: Comparison between a positive allosteric modulator and an orthosteric agonist.
Polyclonal T-cell reconstitution of X-SCID recipients after in utero transplantation of lymphoid-primed multipotent progenitors
Although successful in utero hematopoietic cell transplantation (IUHCT) of X-linked severe combined immune deficiency (X-SCID) with enriched stem and progenitor cells was achieved more than a decade ago, it remains applied only in rare cases. Although this in part reflects that postnatal transplantations have overall given good results, there are no direct comparisons between IUHCT and postnatal t
Associations between malaria and MHC genes in a migratory songbird
High-speed stereo DPIV measurement of wakes of two bat species flying freely in a wind tunnel
Previous studies on wake flow visualization of live animals using DPIV have typically used low repetition rate lasers and 2D imaging. Repetition rates of around 10 Hz allow similar to 1 image per wingbeat in small birds and bats, and even fewer in insects. To accumulate data representing an entire wingbeat therefore requires the stitching-together of images captured from different wingbeats, and a
Genetic variation in two endangered Acrocephalus species compared to a widespread congener: estimates based on functional and random loci
Substantial genetic variation is hypothesised to be necessary for the long-term survival of species. Therefore, a major aim in conservation is to maintain and restore variation in small and endangered populations. However, in most populations the amount of genetic variation and, thus, the potential threats posed by limited variation are unknown. In the present study, we assess genetic variation, b
