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GARD – Genomic Allergen Rapid Detection : From Biomarker Discovery towards a State-of-the-art Testing Platform for Chemical Sensitizers
Chemical hypersensitivity reactions induced in the skin or in the respiratory tract are important health concerns and develops following repeated exposure to certain chemicals, termed sensitizers. To prevent such hazardous compounds from entering the consumer market, legal frameworks within EU require chemicals to be tested for their capacity to induce hypersensitivity. This type of testing has trChemical hypersensitivity reactions induced in the skin or in the respiratory tract are important health concerns and develops following repeated exposure to certain chemicals, termed sensitizers. To prevent such hazardous compounds from entering the consumer market, legal frameworks within EU require chemicals to be tested for their capacity to induce hypersensitivity. This type of testing has tr
Protein structure alignment using mean field annealing
Unraveling functional and ancestral relationships between proteins as well as structure prediction procedures require powerful protein alignment methods. This paper describes the use of fuzzy alignments when matching protein structures. The method use mean-field annealing optimization of fuzzy alignment variables, based on a cost expressed in terms of distances between aligned atoms and of gaps. T
Sanningssökare - En bayesiansk bevisvärderingsanalys av ej styrkta rekvisit i friande mål om människohandel
Syftet med arbetet har varit att, med hjälp av bayesiansk sannolikhetsteori som bevisvärderingsmetod, kritiskt analysera svenska människohandelsmål. Detta har gjorts för att utröna om det förekommer tecken på bristande bevisvärdering från domstolarna som bidrar till att rekvisit ej anses styrkta i dessa mål där någon blir friad, och i utsträckning bidragit till bevisproblematik kring brottet. Syft
The Principle of Non-Refoulement in Swedish Migration Law
Syftet med denna uppsats är att undersöka om Sverige har uppfyllt sina internationella åtaganden gällande efterlevnaden av principen om non-refoulement i svensk migrationsrätt. I generella termer innebär principen om non-refoulement ett verkställighetshinder mot avvisning och utvisning då personen i fråga riskerar att utsättas för tortyr och förföljelse i det mottagande landet. Denna princip kommeThe purpose of this thesis is to assess whether Sweden has fulfilled its obligation to implement the principle of non-refoulement in Swedish migration law. The principle of non-refoulement, in general terms, implies an impediment for execution that obliges a state not to permit removal of a person to a county where he or she is at risk of being subjected to torture or persecution. This principle i
Vertical temperature gradients in apartments with hydronic radiator heating
Analysis of the domain superfamily composition in unicellular and multicellular fungi
Det ryska barnbibliotekets roll och överlevnad i dagens Ryssland : En fältundersökning på barnbiblioteket i Pskov
In an international perspective the Russian children s library is a unique institution, being solely committed to children up to 14 years of age. In Russia of today it is, however, being exposed to hard pressure as the economical and social conditions have changed dramatically since the collapse of the USSR. My interest lies in examining this change of living conditions for the children s librarie
MOA-2010-BLG-523:" Failed Planet"= RS CVn Star
The Galactic bulge source MOA-2010-BLG-523S exhibited short-term deviations from a standard microlensing light curve near the peak of an A(max) similar to 265 high-magnification microlensing event. The deviations originally seemed consistent with expectations for a planetary companion to the principal lens. We combine long-term photometric monitoring with a previously published high-resolution spe
Theoretical oscillator strengths for Sr II and Y III, with application to abundances in the HgMn-type star chi Lupi
Oscillator strengths for selected transitions of Sr II and Y III have been determined using ab initio multiconfiguration Hartree-Fock techniques. The importance of including an accurate treatment of the core-valence correlation is emphasized. The results are used to determine the abundances of Sr and Y in the chemically peculiar star chi Lupi from HST/GHRS Echelle spectra. Overabundances of 2.09 d
The stars of the Galactic center
We consider the origin of the so-called S stars orbiting the supermassive black hole at the very center of the Galaxy. These are usually assumed to be massive main-sequence stars. We argue instead that they are the remnants of low-to-intermediate mass red giants that have been scattered into near-radial orbits and tidally stripped as they approach the central black hole. Such stars retain only low
Neural networks for image-based wavefront sensing for astronomy
We study the possibility of using convolutional neural networks for wavefront sensing from a guide star image in astronomical telescopes. We generated a large number of artificial atmospheric wavefront screens and determined associated best-fit Zernike polynomials. We also generated in-focus and out-of-focus point-spread functions. We trained the well-known “Inception” network using the artificial
Chemical enrichment in the early galaxy
New, precise abundance data for a large number of elements in a growingsample of extremely metal-poor stars are accumulating from the new 8-mtelescopes. Combined with theoretical models, these results advance ourunderstanding of the first generations of stars, whose nucleosynthesisproducts are fossilised in the oldest stars we see today and thus giveclues to the earliest phases of evolution in the
A statistical model for quark fragmentation into mesons with emphasis on vector meson contributions
This paper is the first part of a program to deal with the relative importance of the different effects in a colour dipole field when the field energy is transformed into hadrons according to a statistical scheme with the sole constraints coming from energy and momentum conservation and the requirements of scaling. In this paper we treat the meson distributions from quark fragmentation with partic
Tumor tissue protein signatures reflect histological grade of breast cancer
Histological grade is one of the most commonly used prognostic factors for patients diagnosed with breast cancer. However, conventional grading has proven technically challenging, and up to 60% of the tumors are classified as histological grade 2, which represents a heterogeneous cohort less informative for clinical decision making. In an attempt to study and extend the molecular puzzle of histoloHistological grade is one of the most commonly used prognostic factors for patients diagnosed with breast cancer. However, conventional grading has proven technically challenging, and up to 60% of the tumors are classified as histological grade 2, which represents a heterogeneous cohort less informative for clinical decision making. In an attempt to study and extend the molecular puzzle of histolo
W production in an improved parton-shower approach
In the description of the production properties of gauge bosons (W±, Z0, γ*) at colliders, the lowest-order graph normally is not sufficient. The contributions of higher orders can be introduced either by an explicit order-by-order matrix-element calculation, by a resummation procedure or by a parton-shower algorithm. Each approach has its advantages and disadvantages. We here introduce a method t
Variational auto-encoders with Student’s t-prior
We propose a new structure for the variational auto-encoders (VAEs) prior, with the weakly informative multivariate Student’s t-distribution. In the proposed model all distribution parameters are trained, thereby allowing for a more robust approximation of the underlying data distribution. We used Fashion-MNIST data in two experiments to compare the proposed VAEs with the standard Gaussian priors.
Jorden : En planet bland många
I solsystemet kan vi se åtta planeter, flera dvärgplaneter och mängder av asteroider och kometer kretsande runt Solen. I planetariet kan vi lära oss om Jorden och månen, säsonger och stjärnorna. Vi utforskar solsystemets åtta planeter, lär oss om stjärnbilderna och att bara för att det kallas för "stjärnfall" betyder det inte att stjärnor kan falla från himlavalvet.We have eight planets, quite a few dwarf planets and a lot of asteroids and comets orbiting the Sun. In the planetarium we can learn about the Earth and the Moon, the seasons and the stars. We explore the planets of the solar system, learn about the constellations and discover that just because it is called "a shooting star" does not mean that stars can fall from the skies.
The Meridian S02E01 : The James Webb Space Telescope & an unexpected boat ride
In this first episode of the second season Nic and Rebecca invite Ori Fox to the podcast to discuss the newly launched JWST. Ori is an instrument scientist at the pace Telescope Science Institute (STSI) working on the Mid-Infrared Instrument (MIRI) which is one of four instruments on the James Webb Space Telescope. In this second season of the Meridian we are also bringing you some field reporting
Design and development of electrochemical sensors with application in bioanalysis
Popular Abstract in English There is a continuous search for reliable, robust easy to use, portable and cost effective analytical tools with applications in food industry, biomedicine, environmental monitoring and homeland security. The main focus of the thesis was on the development of electrochemical (bio)sensors designed to detect analytes of key importance from biological matrixes (e.g., fermeThere is a continuous search for reliable, robust, easy to use, portable and cost effective analytical tools with applications in food industry, biomedicine, environmental monitoring and homeland security. The main focus of this thesis is the development of electrochemical (bio)sensors and bioanalysis systems (to be applied in two major fields of interest: food & beverage industry and biomedic
