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The transmembrane protein Dystroglycan is a central element of the dystrophin-associated glycoprotein complex, which is involved in the pathogenesis of many forms of muscular dystrophy. Dystroglycan is a receptor for multiple extracellular matrix (ECM) molecules such as Laminin, agrin and perlecan, and plays a role in linking the ECM to the actin cytoskeleton; however, how these interactions are r
Emission trading schemes (ETS) have emerged as a popular climate policy measure and are increasingly advocated as policy instruments to support the transition to a green economy. Using complementary analytical methods, this research investigated the institutional developments and complexities of the New Zealand Emissions Trading Scheme (NZ ETS). It focuses on (1) institutional experience and admin
The MUI framework supports composition of ad-hoc applications from services available on ad-hoc networked devices. MUI is an open-ended framework, relying on migrating user interfaces and standardized data formats for connecting services, allowing existing devices to be connected to new devices without needing any pre-defined knowledge of their services. We illustrate the benefits of the approach
This paper presents a practical risk analysis method for critical, large-scale IT systems in an organisation. The method is based on reliability block diagram modelling and was adapted to fit the requirements of governmental organisations and to reduce the effort required to capture complex failure behaviour. Through the use of different failure categories the risk analysis can be simplified, the
Support for procedural operations is important in industry. Within the EU/GROWTH project CHEM aimed at developing advanced decision support systems for the process industry, Grafchart, a toolbox for procedure handling based on Grafcet/Sequential Function Charts, will be used to implement a state-transition support toolbox. A brief overview of Grafchart is given, including a new Java version, JGraf
Popular Abstract in Swedish Turismindustrin är numera en av världens absolut största industrier. Den är av central betydelse för ekonomisk utveckling och arbetstillfällen i ett stort antal länder. Det finns dock en baksida: turism leder ofta till exploatering av miljön, och bidrar i många fall till sociala och kulturella problem. Dagens turismindustri är inte förenlig med hållbar utveckling och deTourism has become a leading industry in the world and continues to grow rapidly, contributing essentially to economic growth and employment in many countries. Tourism as it looks today poses serious threats to the environment and considerable social and cultural challenges. The problem addressed by this research lies in the weakness of current concepts and practices in pursuit of sustainable tour
Popular Abstract in Swedish Huvudtanken i svensk välfärdspolitik är att genom generella åtgärder skapa ett samhälle tillgängligt för alla medborgare. Det är därför viktigt att undvika segregering och särlösningar och i stället höja normalverksamhetens standard. Fritidshemmets mål och uppgifter är desamma för alla barn och kvaliteten i verksamheten ska vara så hög att alla barns behov tillgodoses. The main idea behind the Swedish welfare state is to create a society accessible to all citizens by using to general measures. It is, therefore, important to avoid segregation and special solutions, and instead increase the standard of normal activities. The objectives and tasks of day centres for school-age children are the same for all children and the quality of the operations should be of a st
