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Peripheral serotonin levels as a predictor of antidepressant treatment response : A systematic review

There are currently no reliable biomarkers to predict clinical response to pharmacological treatments of depressive disorders. Peripheral blood 5-hydroxytryptamine (5-HT; serotonin) has been suggested as a biomarker of antidepressant treatment response, but there has not been an attempt to systematically summarize and evaluate the scientific evidence of this hypothesis. In this systematic review w

Handling New and Changing Requirements with Guarantees in Self-Adaptive Systems using SimCA

Self-adaptation provides a principled way to deal with change during operation. As more systems with strict goals require self-adaptation, the need for guarantees in self-adaptive systems is becoming a high-priority concern. Designing adaptive software using principles from control theory has been identified as one of the approaches to provide guarantees. However, current solutions can only handle

The Scheimpflug lidar method

The recent several years we developed the Scheimpflug lidar method. We combined an invention from the 19th century with modern optoelectronics such as diode lasers and CMOS array from the 21st century. The approach exceeds expectations of background suppression, sensitivity and resolution beyond known from time-of-flight lidars. We accomplished multiband elastic atmospheric lidars for resolving si

Biogeografisk uppföljning 2019 av dagfjärilar inom habitatdirektivet

Rapporten sammanfattar fjärilsinventeringar utförda 2019 inom Biogeografisk uppföljning som drivs av Naturvårdsverket. I fjällområdet kunde totalt 36 ytor inventeras och sammanlagt noterades 84 högnordiska blåvingar på 17 av de inventerade ytorna och 11 dvärg¬pärlemorfjärilar på 5 ytor. Inga fynd av fjällsilversmygare gjordes på någon av de 3 ytor som inventerades. Svartfläckig blåvinge observerad

QUANTIFYING UNCERTAINTY IN INSAR-DERIVED DISPLACEMENT MEASUREMENTS FOR BRIDGE MONITORING

Bridge monitoring is essential for ensuring their long-term safety, reducing disruptions, and supporting economic and social activities. Traditional monitoring techniques rely on periodic inspections and contact-based sensing systems, which, while effective, have limitations due especially to high installation and maintenance costs. Satellite-based Synthetic Aperture Radar Interferometry (InSAR) o

Decentralized ventilation unit for window frame integration

Swedish National Board of Housing, Building and Planning reported in "Energi i bebyggelsen"that 80 % of the detached houses in Sweden were under-ventilated, and had a flow of 0.23 l/(s·m2) on average instead of, by the code, required 0,35 l/(s·m2). Well known concerns here are lacking indoor environmental quality and a risk of moisture problems in certain rooms and in the envelope. The naturally v

Acoustic focusing of microparticles in two-phase systems - Towards cell enrichment or medium exchange in droplets

We present a method to first laterally position microparticles inside droplets by acoustic forces and then split the droplet into three daughter droplets to achieve a 2+fold enrichment of microparticles inside the center droplet. We show that acoustic forces can be applied to both manipulate polystyrene beads (5 μm) and red blood cells inside droplets. The presented technology opens up for develop

Combined density and size-based sorting in deterministic lateral displacement devices

We present a deterministic-lateral-displacement (DLD) device that extends the capabilities of this traditionally sizebased particle separation technique to also be sensitive to density. By the use of T-shaped posts instead of the normally cylindrical posts the particle trajectory through the device will be a function of its vertical position which in turn is determined by the buoyancy of the parti

Uppföljning efter hjärtstopp - nu finns svenska riktlinjer

Kognitiva och emotionella svårigheter är vanliga hos personer som överlevt ett hjärtstopp. Rutinerna för uppföljning efter hjärtstopp varierar stort mellan olika regioner och sjukhus i Sverige.För att förbättra vården har Svenska HLR-rådets arbetsgrupp för vård efter hjärtstopp tagit fram svenska riktlinjer för uppföljning efter hjärtstopp.According to previous research, a structured cardiac arrest follow-up may contribute to identifying health problems and the potential need of support among survivors and their relatives. However, a survey on post CA care and follow-up in Sweden, reported a lack of structure and major variations among Swedish hospitals. In 2016, Swedish guidelines were published with the aim to improve care. Accord

Fluorescence enhancement from single DNA molecules confined in SiO 2 nanochannels

We demonstrate that the detected emission intensity from YOYO-labeled DNA molecules confined in 180 nm deep Si/SiO2 nanofunnels changes significantly and not monotonically with the width of the funnel, an emission enhancement that is only detected for emitted light polarized parallel to the channel. We explain the enhancement effect as being due to optical phenomena in the channels. The enhancemen

Capillary driven separation on patterned surfaces

Deterministic lateral displacement (DLD) is a powerful bimodal separation scheme [1] based on fluid flow through regular obstacle arrays that in its basic embodiment sends suspended particles in two different directions as a function of size. We show that without the need to seal devices and without the need for fluidic connections or pumps, particle separation can be achieved by the passive flow

Gravitationally driven deterministic lateral displacement devices

Deterministic lateral displacement (DLD) is a powerful bimodal separation scheme [1] based on regular obstacle arrays that in its basic embodiment sends particles in two different directions as a function of size. We add functionality to the technique by including gravitational forces, as a perturbation to particles transported by fluid flow, and as a way of transporting the particles through a st

Shape-based particle sorting - A new paradigm in microfluidics

Conventional fractionation techniques fail to fully benefit from the variety in morphology and shape that is found among biological particles. Although light scattering in conventional FACS gives some information on the size and morphology of a particle, it is generally not capable of giving a definite number on specified dimensions of a small object. We demonstrate an approach where we select whi

Multi-photon lithography on thin films for efficient fabrication of 2D and 2.5D meta-atoms

Direct laser writing (DLW) has arise interest in a variety of fields due to the capabilities that we get from the realization of 2D and 3D structures with high resolution fabrication techniques. Multi-photon lithography (MPL) relies on non-linear absorption effects, making possible the fabrication of metasurfaces with feature size beyond the diffraction limit. A new approach in this direction is t

Typical Values for Active Solar Energy in Urban Planning

There is an urgent need to start generating energy within cities in order to pave the way for a more sustainable and resilient society. Renewable energy by means of active solar energy systems (solar thermal, ST and/or photovoltaics, PV) can be generated using roofs and facades of buildings. In this study, the annual solar energy potential of typical Swedish city blocks was analysed in order to de

Produktkalkylering på ett tillverkande företag

Introduction The company produces different kinds of hearing protection aids, varying from simple plugs to advanced hearing-muffs with built-in electronics. At the department where this thesiswork was executed, hearing-muffs with electronics are produced. The company wishes to analyse the production-costs for some of the products by using an activity-based costing, (ABC). The ABC is expected to re